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Carotenoids have recently received considerable interest because of their potential in delaying or preventing degenerative diseases such as arteriosclerosis, cancer, and aging. In this study we show that the active oxygen species singlet oxygen (1O2) and peroxyl radicals differently affect carotenoid composition and biosynthesis in the yeast Phaffia(More)
Carotenoids occur universally in photosynthetic organisms but sporadically in nonphotosynthetic bacteria and eukaryotes. The primordial carotenogenic organisms were cyanobacteria and eubacteria that carried out anoxygenic photosynthesis. The phylogeny of carotenogenic organisms is evaluated to describe groups of organisms which could serve as sources of(More)
Data Grids are being built across the world as the next generation data handling systems to manage peta-bytes of inter organizational data and storage space. A data grid (datagrid) is a logical name space consisting of storage resources and digital entities that is created by the cooperation of autonomous organizations and its users based on the(More)
When the clinical manifestations of 272 patients with sickle cell anemia are compared with their level of fetal hemoglobin (HbF), the results suggest that there may be a threshold above which HbF is effective in ameliorating the morbidity of this disease. The age of entry of these SS patients into the study ranged from birth to 56 yr; the average length of(More)
Persons with sickle cell anemia who have elevated fetal hemoglobin or lowered erythrocyte mean corpuscular volume are reputed to have less severe clinical manifestations and a greater probability of survival. This study examines the relationship between seven clinical indicators of morbidity in sickle cell anemia and seven hematological parameters that were(More)
Current distributed data management systems implement internal consistency constraints directly within the software. If these constraints change over time, the software must be rewritten. A new approach towards data management system based on the dynamic execution of rules is discussed. By building upon the experiences gained with the Storage Resource(More)