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1. What is the Madden-Julian Oscillation (MJO)? The Madden-Julian Oscillation (MJO) is a tropical disturbance that propagates eastward around the global tropics with a cycle on the order of 30-60 days. The MJO has wide ranging impacts on the patterns of tropical and extratropical precipitation, atmospheric circulation, and surface temperature around the(More)
The U.S. Climate Variability and Predictability (CLIVAR) working group on drought recently initiated a series of global climate model simulations forced with idealized SST anomaly patterns, designed to address a number of uncertainties regarding the impact of SST forcing and the role of land–atmosphere feedbacks on regional drought. The runs were carried(More)
FMRFamide (phenylalanyl-methionyl-arginyl-phenylalanine amide) is a cardioexcitatory peptide recently isolated and identified in molluscan ganglia. Both FMRFamide and 5-hydroxytryptamine (5HT), the cardioexcitatory neurotransmitter in molluscs, were tested on the ventricle of the bivalve Mercenaria mercenaria. Both agents increased myocardial contractility,(More)
Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellular serine protease inhibitors (serpins) is one of the mechanisms by which tumor cells evade cytotoxic(More)
We compared the molecular nature of the rat brain opiate receptor with that of the invertebrate leech, Haemopis marmorata, and the protozoan, Tetrahymena, in order to examine the issue of apparent receptor heterogeneity with respect to biochemical structure. A binding study with rat brain membrane verified that [125I]beta-endorphin [( 125I]beta E), a broad(More)
PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties. PEDF contains a secretion signal sequence, but although originally regarded as a secreted extracellular protein, endogenous PEDF is found in the cytoplasm and nucleus of several mammalian cell(More)
MMPI response protocols for 194 psychiatric patients were scored on the basis of the first 168 items and then on the usual 400 items. The MMPI-168 raw scores were converted to estimates of conventional clinical scale scores. The Ss were divided into 10 major categories on the basis of final clinical diagnosis. Multiple discriminant analysis was used to(More)
A modified liquid encapsulated Czochralski (LEC) process has been developed which yields completely single crystals 22 kg in weight, 110 mm diameter and 435 mm parallel length. These crystals will yield up to 375 wafer/ingot compared with the 50-80 wafers typical of the current 8 kg process. This process moves the production of GaAs substrates from a(More)
This study assessed validity and reliability of the Health Knowledge Inventory-Alpha (HKI-Alpha) in a sample of high school seniors. The HKI-Alpha, a general health knowledge test, consists of 110 multiple choice items covering 11 health content areas. All seniors attending one of four high schools completed HKI-Alpha twice, one week apart. A secondary(More)