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Many enveloped viruses exploit the class E vacuolar protein-sorting (VPS) pathway to bud from cells, and use peptide motifs to recruit specific class E VPS factors. Homologous to E6AP COOH terminus (HECT) ubiquitin ligases have been implicated as cofactors for PPXY motif-dependent budding, but precisely which members of this family are responsible, and how(More)
Recent advances in wireless communication and microelectronics have enabled the development of low-cost sensor devices leading to interest in large-scale sensor networks for military applications. Sensor networks consist of large numbers of networked sensors that can be dynamically deployed and used for tactical situational awareness. One critical challenge(More)
We present the design of the Snackbot, a robot that will deliver snacks in our university buildings. The robot is intended to provide a useful, continuing service and to serve as a research platform for long-term Human-Robot Interaction. Our design process, which occurred over 24 months, is documented as a contribution for others in HRI who may be(More)
The detection and tracking of embedded malicious subnets in an active social network can be computationally daunting due to the quantity of transactional data generated in the natural interaction of large numbers of actors comprising a network. In addition, detection of illicit behavior may be further complicated by evasive strategies designed to camouflage(More)
The electrocardiogram (ECG) is an electrophysiologic signal that conveys signature biometric data about individuals. While this signal varies across time and with mental state, and is susceptible to noise artifact, this paper presents an approach for classifying individuals that is robust to these signal properties and noise sources. To show maximal(More)
Executive Summary Degenerative retinal diseases (RP) and age-related mac-ular degeneration (AMD) affect the normal function of photoreceptor cells in the retina, causing patients with severe afflictions to develop extensive vision loss. Our team worked with Professor Shawn Kelly, Ph.D. from Carnegie Mellon University to develop a retinal prosthesis for(More)
Our work explores the vision of integrating 3d data collected through photogrammetry into the source of the information in a physical space leveraging Mixed Reality (MR) interface platform. As a proof-of-concept prototype design, we show augmentation of the 3D data associated with the physical surrounding using HoloLens and Photogrammetry technique. Our(More)
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