Wayne Akers

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Objectives The β-lactamase inhibitor relebactam can restore imipenem activity against imipenem non-susceptible pathogens. Methods To explore relebactam's safety, tolerability and efficacy, we conducted a randomized (1:1:1), controlled, Phase 2 trial comparing imipenem/cilastatin+relebactam 250 mg, imipenem/cilastatin+relebactam 125 mg and(More)
Changes in planktonic microfossil assemblages in Atlantic and Pacific sediment cores of Late Cenozoic age correspond in a general way with a horizon recognized in neritic sediments of the northern Gulf of Mexico. Geological evidence from the Gulf Coast indicates that the changes occurred near theend of the Aftonian interglaciation of the early Pleistocene(More)
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