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The organization of backward projections from the anterior part of the inferotemporal cortex (area TE) to the posterior part of the inferotemporal cortex (area TEO) was studied in the macaque monkey by using the anterograde tracer Phaseolus vulgaris-leucoagglutinin (PHA-L). The objectives of the study were to investigate this backward projection and to(More)
We can discriminate visual objects at multiple levels, from coarse categorization to individual identification. It is not known how the brain adapts to the varying levels of discrimination required in different behavioral contexts. In the present study, we investigated whether the stimulus selectivity of neuronal responses in the monkey inferotemporal(More)
Choosing an action that leads to a desired goal requires an understanding of the linkages between actions and their outcomes. We investigated neural mechanisms of such goal-based action selection. We trained monkeys on a task in which the relation between visual cues, action types, and reward conditions changed regularly, such that the monkeys selected(More)
Impairment of insulin-stimulated GLUT4 translocation in skeletal muscle and adipose tissue in the Tsumura Suzuki obese diabetic mouse: a new genetic animal model of type 2 diabetes Abstract Background: In skeletal muscle and adipocytes, insulin-stimulated glucose transport has been known to occur through the translocation of glucose transporter (GLUT) 4(More)
Diffuse flash stimuli applied to the ocular fundus evoke light reflectance decreases of the fundus illuminated with infrared observation light. This phenomenon, which is independent of the photopigment bleaching observed as an increase in the reflectance of visible light, is called intrinsic signals. Intrinsic signals, in general, are stimulus-evoked light(More)
Bone morphogenetic proteins (BMPs) control the expressions of many genes involved in bone formation. On the basis of our hypothesis that BMP2 stimulation-regulated gene expression plays a critical role in osteoblast differentiation, we performed genome-wide screening of messenger RNA from BMP2-treated and -untreated C2C12 cells using a DNA microarray(More)
PURPOSE Various methods have been used to obtain a topographic map of bleached photopigments in human retinas in the past. The purpose of this study was to determine whether the bleaching topography of the photoreceptors could be obtained by snapshot imaging reflectometry. METHODS Four to five fundus photographs of one rhesus monkey and three healthy(More)
Visual expertise in discriminating fine differences among a group of similar objects can be obtained through extensive long-term training. Here we investigated the neural bases of this superior capability. The inferotemporal cortex, located at the final stage along the ventral visual pathway, was a candidate site in monkeys because cells there respond to(More)
Discussion Papers are a series of manuscripts in their draft form. They are not intended for circulation or distribution except as indicated by the author. For that reason Discussion Papers may not be reproduced or distributed without the written consent of the author. Abstract As the Japanese population structure changes, health care and long-term care(More)
PURPOSE To investigate the properties and origin of retinal intrinsic signals by functional optical coherence tomography (fOCT) in macaque retinas. METHODS We modified a spectral domain OCT system to be able to give short-duration flashes or continuous light stimulation to the retina of three adult macaque monkeys (Macaca mulatta) under general(More)