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Since sulfation is the main metabolic pathway of troglitazone, accounting for about 70% of the metabolites detected in human plasma, we have aimed to identify human cytosolic sulfotransferases catalyzing the sulfation of troglitazone and to examine a possible role of the sulfation in the cytotoxicity observed in cell lines of human origin (HepG2 and Hep3B).(More)
PURPOSE Unilateral chewing requires a greater number of chewing strokes up to the point of the first swallowing. The rate of storage of ground food particles in the oral vestibule is said to be high during unilateral chewing. However, influence of the masticatory method, that is free-sided or unilateral chewing, involved in masticatory efficiency has not(More)
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