Wasiu Opeyemi Oduola

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In this paper, we review multiscale modeling for cancer treatment with the incorporation of drug effects from an applied system's pharmacology perspective. Both the classical pharmacology and systems biology are inherently quantitative; however, systems biology focuses more on networks and multi factorial controls over biological processes rather than on(More)
Because cancer usually involves multiple genes and pathways, combination therapy is considered as a promising approach for cancer treatment. However, when multiple drugs are taken by a patient simultaneously, toxicity becomes a concern. A potential solution is to give the drugs sequentially rather than simultaneously. In this study, we try to explore the(More)
OBJECTIVE Tumorigenesis is due to uncontrolled cell division arising from mutations and alterations in the proliferative controls of the cell population. The fight against tumor growth and development has often relied on combination therapy which has been acclaimed as one of the main standards of care in cancer therapeutics and prevention of drug-related(More)
As cancer growth and development typically involves multiple genes and pathways, combination therapy has been touted as the standard of care in the treatment of cancer. However, drug toxicity becomes a major concern whenever a patient takes 2 or more drugs simultaneously at the maximum tolerable dosage. A potential solution would be administering the drugs(More)
This study takes advantage of the ability of Physical-Layer Network Coding (PNC) to embrace electromagnetic interference, improve spectral efficiency and achieve throughput optimality in a femtocell operated as a relay. Specifically, we make a case for a femtocell operating as a relay and utilizing PNC to eliminate the interference that exists between(More)
The challenge of mitigating the Uplink (UL) interference in a two-tier heterogeneous network could be significantly improved by employing Physical-Layer Network coding (PNC) at a Home NodeB (HNB). This paper makes a case for a macrocell femtocell overlay network that utilizes PNC to mitigate the UL interference at the HNB. In closed subscriber group (CSG)(More)
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