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BACKGROUND Bladder cancer is one of the most common malignancies occurring worldwide. No published data exists on bladder cancer in Sri Lanka. The objective of the study was to determine the clinicopathological characteristics of histologically confirmed transitional cell carcinoma (TCC) of the bladder in Sri Lanka. METHODS Three hundred and one patients(More)
Breast Cancer is the most commonly diagnosed cancer among Sri Lankan women. Germline mutations in the susceptibility genes BRCA1 and BRCA2 in hereditary breast/ovarian cancer, though low in prevalence, are highly penetrant and show geographical variations. There have been only a few reports from Asia on mutations in BRCA1/2 genes and none from Sri Lanka. A(More)
OBJECTIVE To document clinical features of propanil poisoning and discuss treatment. DESIGN, SETTING AND PATIENTS Five patients treated in the University medical unit at the Karapitiya teaching hospital over the past two years. INTERVENTIONS AND MEASUREMENTS Relevant laboratory investigations were done. The patients were treated on accepted lines. (More)
INTRODUCTION Growth hormone releasing hormone receptor (GHRH-R) codon 72 mutation is recognised as a common genetic cause of growth hormone deficiency (GHD) in the Indian subcontinent resulting in a characteristic lean phenotype. Genetic studies have not been previously carried out in Sri Lankans with GHD. METHODS Patients with GHD presenting to a(More)