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Innate lymphoid cells (ILCs) play a central role in the response to infection by secreting cytokines crucial for immune regulation, tissue homeostasis, and repair. Although dysregulation of these systems is central to pathology, the impact of HIV-1 on ILCs remains unknown. We found that human blood ILCs were severely depleted during acute viremic HIV-1(More)
An outbreak of respiratory diphtheria occurred in two health districts in the province of KwaZulu-Natal in South Africa in 2015. A multidisciplinary outbreak response team was involved in the investigation and management of the outbreak. Fifteen cases of diphtheria were identified, with ages ranging from 4 to 41 years. Of the 12 cases that were under the(More)
"Induced hydrolysis" a new hydrolytic activity, was found by measuring AMP-production during aminoacylation of tRNAPhe-CCA by yeast phenylalanyl-tRNA synthetase in the presence of tRNAPhe-CC under conditions of low ionic strength at pH 8.5. Experiments using the elongation factor Tu . GTP provide evidence that transfer of phenylalanine to the tRNAPhe-CCA is(More)
nicht vorliegend. Acta Chir. Aus t r iaca Vol. 32 Supp lemen t No 183 2000 45 145. BRCA1 Sequence Variants in 268 Austrian Breast and Ovarian Cancer Families Teresa Wagner, R. M6slinge~; E. Fleischrnann, G. Langbauer, D. Muhr, M. Hareter, P. Kofler. C. Zielinski, P. Oefner (The Austrian Hereditary Breast and Ovarian Cancer Group) Background: Since the(More)