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In this paper, an extension of kernel Fisher discriminant (KFD), namely, distributed KFD (DKFD), is proposed for multi-class cases. Unlike the generalized discriminant analysis (GDA) which deals with all classes synchronously, DKFD uses a cost—normalized KFD for two-class problems and thereby covers the whole system by the KFD units. Based on DKFD,(More)
BACKGROUND AND PURPOSE Thromboxane A2 (TXA2) receptors (TP) interact with the ligand TXA2 to induce platelet aggregation and regulate hemostasis. Recently TP-mediated signaling has been suggested to function in multiple cell types in the brain. In this report, we aim to study the expression and physiological role of TP in microglia, in particular after(More)
In radar HRRP target recognition, the quality and quantity of Discriminant Information (DI), which one is more important? Accompanied with this issue, the paper proceeds to delve into DI analysis, and accordingly, three fundamental DI extraction models are proposed, i.e., PGA, PIB and AIB. Among these models, PIB and AIB both aim to obtain Between-class DI(More)
OBJECTIVE To compare the accuracy of formula 1/2ABC with 2/3SH on volume estimation for hypertensive infratentorial hematoma. METHODS One hundred and forty-seven CT scans diagnosed as hypertensive infratentorial hemorrhage were reviewed. Based on the shape, hematomas were categorized as regular or irregular. Multilobular was defined as a special shape of(More)
In an Automatic Target Recognition (ATR) system, target recognition-makers need assistance to determine which class a new High Resolution Range Profile (HRRP) belongs to. Note that the HRRP data can be obtained from an Open Database (ODB) freely, we present a new Multi-Agent System (MAS) model in which specialized intelligent agents, namely Individual(More)
Binding of thromboxane A2 (TXA2) to its receptor TXA2R modulates thrombosis/hemostasis and plays a vital role in the pathogenesis of cerebral infarction (CI). In this study, we investigated the relationship between TXA2R polymorphisms and CI in Chinese Han population and the effect on platelet function by these polymorphisms. Polymerase chain reaction and(More)
Radar target identification using high resolution range profile (HRRP), the target length is an important feature due to that it can reduce the time of identification and mitigate noise redundancy. Traditional threshold methods with the different operators are highly sensitive to noise. In this paper, we proposed an adaptive difference operator for target(More)
In this paper, we consider the problem of parameters estimation of coherently distributed (CD) sources using doublet parallel uniform linear array (ULA) in the presence of mutual coupling. Unlike the mutual coupling matrix of ULA, the mutual coupling matrix of doublet parallel uniform linear array (ULA) is only symmetric but not Toeplitz. Aiming at this(More)
  • Fang Fang, Wanlin Yang, +11 authors Chengbiao Wu
  • 2017
Recent studies have demonstrated that hyperphosphorylation of tau protein plays a role in neuronal toxicities of α-synuclein (ASYN) in neurodegenerative disease such as familial Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and Parkinson's disease. Using a transgenic mouse model of Parkinson's disease (PD) that expresses GFP-ASYN driven by the(More)