Wang Xuezhen

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Hereditary spastic paraplegia (HSP) is a group of neurodegenerative and inherited disorders characterized by progressive lower limb spasticity and weakness resulting from the dysfunction of the corticospinal tracts with a prevalence of 1.8/100,000 in most populations. At present, more than 70 HSP loci (SPG1–SPG72) and more than 50 mutated gene products have(More)
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