Wang Wei

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BACKGROUND MiRNA-21 was previously reported to be up-regulated in many kinds of cancer. In the present study, we want to investigate the potential role of miRNA-21 in non-small cell lung cancer. MATERIALS AND METHODS Expression of miRNA-21 was detected in 60 non-small cell lung cancer (NSCLC) samples and adjacent histologically normal tissue using(More)
Whole exome sequencing in two-generational kindred from Bangladesh with early onset spasticity, mild intellectual disability, distal amyotrophy, and cerebellar atrophy transmitted as an autosomal recessive trait identified the following two missense mutations in the EXOSC3 gene: a novel p.V80F mutation and a known p.D132A change previously associated with(More)
BACKGROUND High post-operative recurrence and poor prognosis are likely to be related to the infiltrative growth of the glioblastoma multiforme (GBM). OBJECTIVES The primary objective of this study is to investigate the possible synergistic effect of the combined treatment of gamma knife radio-surgery (GKRS) and gene therapy for GBM and secondary(More)
(Received) Solvation is essential for protein activities. To study internal solvation of protein, site-directed mutagenesis is applied. Intrinsic fluorescent probe, tryptophan, is inserted into desired position inside protein molecule for ultrafast spectroscopic study. Here we review this unique method for protein dynamics researches. We introduce the(More)
Saw palmetto extract can induce the apoptosis of pros-tate cancer cells. The aim of the present study was to investigate the effect of saw palmetto extract on the phosphatidylinositol 3-kinase (PI3K)/Akt signaling transduction pathway in human glioma U87 and U251 cell lines. Suspensions of U87 and U251 cells in a logarithmic growth phase were seeded into(More)
A rapid and accurate method of quantifying heavy metal pollution in commercial traditional Chinese medicines (TCMs) is described. The method uses modified wet digestion for sample preparation and atomic absorption spectrophotometry for detecting the content of copper (Cu), cadmium (Cd), arsenic (As), lead (Pb) and mercury (Hg). The determination limits of(More)
  • Jiang Xiangyuan, Zhang Huanshui, Wang Wei
  • 2011
A scalar-based information fusion(IF) smoother based on a modified biased Kalman filter(BKF) and maximum likelihood estimation(MLE) is proposed for ranging error mitigation with both the time of arrival(TOA) and received signal strength(RSS) measurement data in ultra wide band(UWB) system to improve the ranging accuracy. The ranging protocl of IEEE(More)
Both improper initialization and fake Gaussian components are critical problems in GMM-based foreground detection. The former can lead to a poor local maximum, while the latter invokes unhandled disturbance. To eliminate these destructive impacts, two kinds of feedback knowledge are introduced: positive and negative prior. For appropriate initialization,(More)