Wan-yuan Chen

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OBJECTIVE To study the expression and clinical significance of P-gp, GST-pi and Topo II alpha in gastric and colorectal cancers. METHODS The expression of P-gp, GST-pi and Topo II alpha in 83 cases with gastric or colorectal cancer were examined by immunohistochemistry S-P. RESULTS The positive expression rates of P-gp, GST-pi, Topo II alpha in normal(More)
BACKGROUND Epidemiologic evidence suggests that chronic inflammation and/or chronic infection is associated with cancer development, and the inflammatory process may play a crucial role in the carcinogenesis and prognosis of colorectal cancer (CRC). Substance P (SP) belongs to the family of tachykinins and acts as an immunomodulator, binding to the(More)
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