Learn More
OBJECTIVE Increased activity of the innate immune system has been implicated in the pathogenesis of the dyslipidemia and insulin resistance associated with obesity and type 2 diabetes. In this study, we addressed the potential role of Kupffer cells (liver-specific macrophages, KCs) in these metabolic abnormalities. RESEARCH DESIGN AND METHODS Rats were(More)
Pain influences many aspects of daily living and effective analgesics should reinstate normal spontaneous daily behaviours. Experiments are described herein which show that the innate, spontaneous behaviour of burrowing by rats, which can be simply and objectively assessed by measuring the amount of gravel left in a hollow tube 1 h after presentation to the(More)
Systemic lupus erythematosus (SLE) is associated with premature atherosclerosis. Increasing arterial stiffness is closely associated with atherosclerotic cardiovascular diseases, and pulse wave velocity (PWV) is considered to be an indicator of arterial stiffness. The objective of this study was to identify the relationship between brachial-ankle pulse wave(More)
CCAAT/enhancer-binding protein beta (C/EBPbeta) plays a key role in initiation of adipogenesis in adipose tissue and gluconeogenesis in liver; however, the role of C/EBPbeta in hepatic lipogenesis remains undefined. Here we show that C/EBPbeta inactivation in Lepr(db/db) mice attenuates obesity, fatty liver, and diabetes. In addition to impaired(More)
Cerebral osmoreceptors mediate thirst and neurohypophyseal secretion stimulated by increases in the effective osmolality of plasma (P(osmol)). The present experiments determined whether an intragastric load of hypertonic saline (ig HS; 0.5 M NaCl, 4 ml) would potentiate these responses before induced increases in P(osmol) in the general circulation could be(More)
Mobility modelling is an essential component of wireless and mobile networking research. Our proposed Agenda Driven Mobility Model takes into consideration a person's social activities in the form of agenda (when, where and what) for motion generation. The model provides a framework for translating social agendas into a mobile world. Using the data from(More)
Agroforestry, as one of integrated approaches to biodiversity conservation, has received attention. But the methods to evaluate this contribution are rare. The present study focuses on the method development for quantification of effects of agroforestry on biodiversity conservation. It includes identifying the functional groups of agroforestry components,(More)
Many methods have been proposed to solve the image classification problem for a large number of categories. Among them, methods based on tree-based representations achieve good trade-off between accuracy and test time efficiency. While focusing on learning a tree-shaped hierarchy and the corresponding set of classifiers, most of them [11, 2, 14] use a(More)
OBJECTIVE To investigate the prevalence of Entamoeba gingivalis infection in college students in Tangshan, and analyze the relationship between the infection and human behaviors. METHODS 551 students of grades 1-3 from six colleges in Tangshan received questionnairing, which covered the oral health state, teeth-brushing, xylitol gum-chewing, diet(More)