Wan-Chen Ku

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PURPOSE To investigate the expression and pivotal role of matrix metalloproteinase (MMP)-9 in the ex vivo expansion of human limbal explants with or without amniotic membrane (AM). METHODS Corneoscleral buttons were cultured on intact, denuded AM or plastic dishes for 3 weeks. To determine the role of MMP-9 in cell migration, either the MMP inhibitor(More)
BACKGROUND To determine the outcome of central retinal vein occlusion (CRVO) in pre-existing glaucoma and the predisposing factors of developing neovascular glaucoma (NVG). METHODS We retrospectively assessed a pre-existing glaucoma CRVO group and a non-glaucoma CRVO group to elucidate the demographics, clinical course and ocular parameters of these two(More)
PURPOSE The most common ocular adverse event following the use of cyclosporine A (CsA) 0.05% ophthalmic emulsion is ocular burning (17%). Other adverse effects that have been reported include conjunctival hyperemia (1-5%), discharge, epiphora, eye pain, foreign body sensation, pruritus, stinging and blurred vision. Here, we report a specific side effect of(More)
The use of antimetabolites in filtration surgery, cystic, large, leaking blebs often lead to complications. We report a case of glaucoma that received amniotic membrane transplanta-tion for repairing the exuberant bleb. This female patient had a history of several eye surgeries , including a scleral buckle and cyclocryotherapy for one eye and the other(More)
BACKGROUND To eliminate complications of peribulbar and retrobulbar anesthesia and to achieve efficacy and safety for topical anesthesia with cataract surgery. METHODS We performed clear corneal phacoemulsification with foldable intraocular lens (IOL) implantation under topical anesthesia using preservative-free 2% lidocaine drops, without intracameral(More)
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