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'Shed' furin: mapping of the cleavage determinants and identification of its C-terminus.

• Barbara Plaimauer, Georg Mohr, Waltraud Wernhart, Micah W Himmelspach, Friedrich Karl Dorner, Uwe Schlokat
• The Biochemical journal
• 2001

The human endoprotease furin is involved in the proteolytic maturation of the precursor molecules of a wide variety of bioactive proteins. Despite its localization in the membranes of the trans-Golgi… (More)

Modulation of ADAMTS13 secretion and specific activity by a combination of common amino acid polymorphisms and a missense mutation.

• Barbara Plaimauer, Jakob Fuhrmann, +7 authors Friedrich Scheiflinger
• Blood
• 2006

Sequence analysis of the ADAMTS13 locus of 2 patients with hereditary thrombotic thrombocytopenic purpura (TTP) revealed the homozygous presence of 4 single nucleotide polymorphisms (SNPs) (R7W,… (More)

Strategies for recombinant Furin employment in a biotechnological process: complete target protein precursor cleavage

• Alexandra Preininger, Uwe Schlokat, +9 authors Friedrich Karl Dorner
• Cytotechnology
• 1999

Coagulation factors, amongst many other proteins, often require posttranslational endoproteolytic processing for maturation. Upon high yield expression of recombinant forms of these proteins,… (More)

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