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A growing trend among clinical studies is the use of heart rate monitors (HRMs) for assessment of heart rate variability (HRV). These instruments offer a convenient alternative to traditional electrocardiographs (ECGs) for recording and processing of R–R data. Reports on the validity of such systems are, however, conflicting. This study aimed to assess the(More)
Despite mounting reports about the negative effects of chronic occupational stress on cognitive and emotional functions, the underlying mechanisms are unknown. Recent findings from structural MRI raise the question whether this condition could be associated with a functional uncoupling of the limbic networks and an impaired modulation of emotional stress.(More)
BACKGROUND Insomnia-type sleep disturbances are frequent among patients suffering from stress-related exhaustion disorder. However, clinical observations indicate that a subgroup suffer from sleep lengths frequently exceeding 9 hours, coupled with great daytime sleepiness. AIMS The aim of the present study was to investigate differences in(More)
OBJECTIVES To use simple measures of laterality and hand control that can identify a greater risk of poorer scholastic ability, potentially signalling suboptimal hemispheric lateralisation. DESIGN Analysis of material from a birth cohort study. SETTING Members of the National Child Development Study, a British birth cohort study following people born in(More)
OBJECTIVE To identify whether measures of childhood physical control and coordination as markers of neurological function are associated with obesity in adults. DESIGN Longitudinal birth cohort study. SETTING National child development study in Great Britain. PARTICIPANTS 11,042 people born during one week in 1958. MAIN OUTCOME MEASURE Obesity at(More)
Dietary behaviour can modify the risks for coronary heart disease (CHD). Dietary fat contributes to the sensory characteristics of many foods, but there are individual differences in liking for regular and reduced fat products. Preference for dietary fat might differ between healthy individuals and those of diagnosed CHD status. Preference for full-fat(More)
OBJECTIVE To investigate if unemployment during an economic downturn is associated with mortality, even among men with markers of better health (higher cognitive function scores and qualifications), and to assess whether the associations vary by age at unemployment. DESIGN Longitudinal register-based cohort study. SETTING Study entry was in 1990 and(More)
OBJECTIVES The authors investigated self-perceived psychosomatic health in young people (10-24 years of age) in Sweden and analysed different samples during the years 2005 and 2007-2010 via a community website. DESIGN Repeated cross-sectional surveys: (1) single question on a single day in 2005. (2) One specific question delivered on each of eight(More)
BACKGROUND We prospectively and longitudinally determined the effects of childhood obesity on arterial stiffening and vascular wall changes. Changes in arterial stiffness measured as pulse wave velocity (PWV) and vascular morphology of the radial (RA) and dorsal pedal arteries (DPA) were examined in obese adolescents compared to lean subjects in a 5-year(More)
The aim of this paper was to provide an overview of the literature on clinically significant burnout, focusing on its assessment, associations with sleep disturbances, cognitive impairments, as well as neurobiological and physiological correlates. Fifty-nine English language articles and six book chapters were included. The results indicate that exhaustion(More)