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  • Laura Gribaldo, Alessandra Gennari, +5 authors Irmela Ruhdel
  • Medicine
  • Alternatives to laboratory animals : ATLA
  • 2005
  • 1. Inventory of methods currently available From the regulatory point of view, the main objective of acute toxicity testing is basically to classify chemicals according to their intrinsic toxicity asContinue Reading
  • Matthias J. Wieser, Guido Stadler, +7 authors Regina Grillari‐Voglauer
  • Medicine, Biology
  • American journal of physiology. Renal physiology
  • 2008 (First Publication: 1 November 2008)
  • Telomere-dependent replicative senescence is one of the mechanisms that limit the number of population doublings of normal human cells. By overexpression of telomerase, cells of various origins haveContinue Reading
  • Sinikka Prajczer, Ursula Heidenreich, Walter Pfaller, Peter Kotanko, Karl Lhotta, Paul Jennings
  • Medicine
  • Nephrology, dialysis, transplantation : official…
  • 2010 (First Publication: 1 June 2010)
  • BACKGROUND Uromodulin (also known as Tamm-Horsfall protein) is the most abundant urinary protein in healthy individuals and exhibits diverse functions including prevention of ascending urinary tractContinue Reading
  • Anja Wilmes, Alice Limonciel, +24 authors Paul Jennings
  • Biology, Medicine
  • Journal of proteomics
  • 2013 (First Publication: 1 February 2013)
  • High content omic techniques in combination with stable human in vitro cell culture systems have the potential to improve on current pre-clinical safety regimes by providing detailed mechanisticContinue Reading
  • Thomas Lechleitner, Frederik Klauser, +11 authors Walter Pfaller
  • Materials Science, Medicine
  • Biomaterials
  • 2008 (First Publication: 1 November 2008)
  • Nanocrystalline diamond (NCD) films and nanoparticulate diamond powder (DP) are the two main representatives of diamond at the nanoscale. This study was designed to investigate the suitability ofContinue Reading