Walter Osika

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OBJECTIVE Compared to normal weight adolescents, obese adolescents have lower serum omega-3 (n-3) polyunsaturated fatty acid (PUFA) concentrations, augmented inflammatory activity and endothelial dysfunction. We wanted to assess whether n-3 supplementation increases the serum n-3 PUFA concentration, improves vascular function and morphology, and lowers(More)
A growing trend among clinical studies is the use of heart rate monitors (HRMs) for assessment of heart rate variability (HRV). These instruments offer a convenient alternative to traditional electrocardiographs (ECGs) for recording and processing of R–R data. Reports on the validity of such systems are, however, conflicting. This study aimed to assess the(More)
We constructed a test to assess stress in children and compared it with established measures of depression, anxiety, angel; disruptive behavior, and negative self-perception. A total of 181 children aged between 9 and 12 years were enrolled at various stages of the construction of a new short questionnaire; Stress in Children (SiC). Baseline data, completed(More)
OBJECTIVE To investigate if unemployment during an economic downturn is associated with mortality, even among men with markers of better health (higher cognitive function scores and qualifications), and to assess whether the associations vary by age at unemployment. DESIGN Longitudinal register-based cohort study. SETTING Study entry was in 1990 and(More)
OBJECTIVE Limited data, especially from longitudinal studies, are available regarding vascular health assessment in childhood. In this study, we performed longitudinal and cross-sectional studies in healthy children and adolescents to investigate age- and sex-related differences in vascular functions and vascular response to mental stress. METHODS Pulse(More)
OBJECTIVE Childhood obesity confers an increased risk of vascular changes and adult cardiovascular disease. Using a high-resolution ultrasound technique that enables separation of intimal and medial layers, we examined the intimal thickness (IT) and intimal-medial thickness (IMT) of radial (RA) and dorsal pedal (DPA) arteries and the pulse wave velocity(More)
OBJECTIVE Atherosclerosis begins and progresses during childhood and adolescence. Endothelial dysfunction is one of the earliest abnormalities that can be detected in the development of atherosclerosis. As the determinants of endothelial function in childhood are unknown, we investigated the influence of cardiovascular risk factors on endothelial function(More)
OBJECTIVE We assessed the hypothesis that differences in day and night-time systolic blood pressure (SBP) and heart rate (HR) recordings were smaller in obese versus lean children and adolescents, and whether measurements obtained during a school week or during weekends or holidays influenced these nocturnal falls. We also wanted to determine whether the(More)
OBJECTIVE Psychosocial adversity is a risk factor for cardiovascular disease (CVD) in adults. The authors assessed associations of reactive hyperaemia peripheral arterial tonometry (RH-PAT), a measure of endothelial function predictive of CVD, with self-assessed psychological health among school children. METHODS A total of 248 healthy school children(More)
OBJECTIVE To identify whether measures of childhood physical control and coordination as markers of neurological function are associated with obesity in adults. DESIGN Longitudinal birth cohort study. SETTING National child development study in Great Britain. PARTICIPANTS 11,042 people born during one week in 1958. MAIN OUTCOME MEASURE Obesity at(More)