Wale A R Sulaiman

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OBJECTIVES We review the state-of-the-art neurobiology of nerve injury and regeneration, especially as it relates to return of useful function in patients who have sustained injuries to large nerve trunks such as the brachial plexus. METHODS This review focuses on research conducted in our laboratory at Ochsner and at other laboratories related to the(More)
OBJECTIVES Although peripheral nerves can regenerate after traumatic injury, functional recovery is often suboptimal, especially after injuries to large nerve trunks such as the sciatic nerve or brachial plexus. Current research with animal models suggests that the lack of functional recovery resides in the lack of sufficient mature axons reaching their(More)
OBJECTIVE AND IMPORTANCE Our patient's symptomatology, history, physical examination, diagnosis, management, and functional outcome 1 year after surgical repair is presented and discussed in light of the current literature on lipofibrohamartomas. CLINICAL PRESENTATION A 3-year-old boy presented to the Louisiana State University Nerve Clinic for evaluation(More)
We review the biology and role of transforming growth factor beta 1 (TGF-β1) in peripheral nerve injury and regeneration, as it relates to injuries to large nerve trunks (i.e., sciatic nerve, brachial plexus), which often leads to suboptimal functional recovery. Experimental studies have suggested that the reason for the lack of functional recovery resides(More)
When spinal cord injury (SCI) occurs, injured cells must survive and regenerate to close gaps caused by the injury and to create functional motor units. After peripheral nerve injury, Wallerian degeneration in the distal nerve stump creates a neurotrophic and growth-supportive environment for injured neurons and axons via Schwann cells and secreted(More)
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