Walburgis Heinicke

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BACKGROUND Huntington's disease (HD) is a rare triplet repeat (CAG) disorder. Advanced, multi-centre, multi-national research frameworks are needed to study simultaneously multiple complementary aspects of HD. This includes the natural history of HD, its management and the collection of clinical information and biosamples for research. METHODS We report(More)
Several candidate modifier genes which, in addition to the pathogenic CAG repeat expansion, influence the age at onset (AO) in Huntington disease (HD) have already been described. The aim of this study was to replicate association of variations in the N-methyl D-aspartate receptor subtype genes GRIN2A and GRIN2B in the "REGISTRY" cohort from the European(More)
Immunobiological action holds a firm position in veterinary legislation of the GDR with regard to the prevention and control of zoonoses, parasitoses, and other risk factors. Here are some of the conditions which have to be satisfied for systematic and purpose-oriented application of live vaccines: (a) Stringent procedures and rules for testing and(More)
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