Wajid Khan

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PURPOSE To determine whether or not there is an association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with disease in cohorts of primary open-angle glaucoma (POAG) and primary closed-angle glaucoma (PCAG) from Pakistan. METHODS This was a prospective study consisting of 150 patients (90 POAG and 60 PCAG) and 70 control(More)
PURPOSE To investigate the methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C genotypes and plasma concentrations of total homocysteine (tHcy) in Pakistani patients with primary open angle glaucoma (POAG) and primary closed angle glaucoma (PCAG). METHODS This was a prospective case-control study. A total of 295 patients (173 POAG, 122 PCAG) and(More)
In this paper Haar wavelets and hybrid functions have been applied for numerical solution of double and triple integrals with variable limits of integration. This approach is the generalization and improvement of the method [31] where the numerical method is only applicable to the integrals with constant limits. Apart from generalization of the method [31],(More)
PURPOSE Matrix metalloproteinases (MMPs) play an important role in remodeling of the extracellular matrix during development and growth of various tissues including the eye. Various functional polymorphisms in MMPs have been implicated in the pathogenesis of different types of glaucoma. The aim of the present study was to investigate the role of various(More)
PURPOSE Despite the different etiology of primary open angle glaucoma (POAG), primary angle closure glaucoma (PACG), and pseudoexfoliative glaucoma (PEXG), several studies have suggested that these forms of glaucoma have overlapping genetic risk factors. Therefore, the aim of this study was to evaluate the role of genetic variants recently associated with(More)
Capital structure changes and financial performance are of central importance to judge the overall returns of the firms and more importantly to know whether stock returns are sensitive to change in capital structure. To quantify such impact, stock return has been taken as dependent variable and debt to equity, return on equity ratio, cash flow ratio,(More)
OBJECTIVE To investigate the barriers and facilitators of an effective implementation of an outcome monitoring and feedback system in a UK National Health Service psychological therapy service. METHOD An outcome monitoring system was introduced in two services. Enhanced feedback was given to therapists after session 4. Qualitative and quantitative methods(More)
BACKGROUND Recently nonsynonymous coding variants in the ankyrin repeats and suppressor of cytokine signaling box-containing protein 10 (ASB10) gene were found to be associated with primary open angle glaucoma (POAG) in cohorts from Oregon and Germany, but this finding was not confirmed in an independent cohort from Iowa. The aim of the current study was to(More)
The human Vg9Vδ2 T cells are a unique T cell type, and recent studies of the biology of Vg9Vδ2 T cells emphasize the potential exploitation of these cells in immunother-apy of cancer. Vg9Vδ2 T cells exhibit dual functionality in that they are both antigen-presenting cells and cyto-toxic towards cancer cells. We have been able to show that Vg9Vδ2 T cells can(More)
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