Wael M Y Mohamed

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BACKGROUND Organophosphates (OPs) represent the most widely used class of pesticides. Although perceived as low toxicity compounds compared to the previous organochlorines, they still possess neurotoxic effects both on acute and delayed levels. Delayed neurotoxic effects of OPs include OPIDN and OPICN. The mechanisms of these delayed effects have not been(More)
Medicine did not develop overnight. The civilizations of Egypt, Greece, Rome, Persia, India, China and the European Renaissance took up the responsibility of the flame of medical development. During the Dark Ages the medical flame was taken up by the Arabic-Islamic world. The period between the 7th and 13th centuries has been commonly neglected, despite the(More)
Parkinson's disease (PD) is the most prevalent movement disorder in the world. The major pathological hallmarks of PD are death of dopaminergic neurons and the formation of Lewy bodies. To the moment, there is no cure for PD; current treatments are symptomatic. Investigators are searching for neuroprotective agents and disease modifying strategies to slow(More)
BACKGROUND In humans, early ID (iron deficiency) may cause impairment of dopamine (DA) metabolism including DA clearance, transporter density, and dopamine receptor (D1 and D2) densities. PURPOSE The present study aims to examine the effects of early ID on the catecholaminergic system within certain brain areas related to attention. METHODS(More)
Thyroxine (T4) enters the brain either directly across the blood-brain barrier (BBB) or indirectly via the choroid plexus (CP), which forms the blood-cerebrospinal fluid barrier (B-CSF-B). In this study, using isolated perfused CP of the sheep by single-circulation paired tracer and steady-state techniques, T4 transport mechanisms from blood into lateral(More)
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It affects the locomotor system, leading to a final severe disability through degeneration of dopaminergic neurons. Despite several therapeutic approaches used, no treatment has been proven to be effective; however, cell therapy may be a promising therapeutic method. In(More)
Problem statement: The problem of testing randomness is motivated by the need to evaluate of the quality of different random number generators used by many practical applications including computer simulations, cryptography and communications industry. In particular, the quality of the randomness of the generated numbers affects the quality of such(More)
Developmental neurotoxicity (DNT) refers to the toxic effects induced by various chemicals on brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have significant effects on brains during early childhood. Some toxicants have been confirmed to induce developmental toxic effects on CNS; however,(More)
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