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Investigating hookworm genomes by comparative analysis of two Ancylostoma species
BackgroundHookworms, infecting over one billion people, are the mostly closely related major human parasites to the model nematode Caenorhabditis elegans. Applying genomics techniques to these… Expand
Molecular cloning and characterization of a C-type lectin from Ancylostoma ceylanicum: evidence for a role in hookworm reproductive physiology.
- A. C. Brown, L. Harrison, +5 authors M. Cappello
- Medicine, Biology
- Molecular and biochemical parasitology
- 1 February 2007
Lectins comprise a family of related proteins that mediate essential cell functions through binding to carbohydrates. Within this protein family, C-type lectins are defined by the requirement of… Expand
gene). Since Friedland and colleagues demonstrated simultaneous CRISPR activity of two inde-pendent sgRNAs on two different loci, I assumed that it would be useful to evaluate/discriminate be-tween… Expand
Allelic spectrum of the RNA guided CRISPR/Cas9 DNA repair events at PAM associated trinucleotide repeat (NGG)n in Caenorhabditis elegans.
- W. Kapulkin
- 10 July 2016
This work describes the experience with implementation of Streptococcus pyogenes Cas9 nuclease, expressed in C. elegans germline. The described work utilizes guide RNA-unc-22-1000… Expand
Comparative study of the grade and stage of chronic hepatitis C with CRP and ALT activity in young adult patients
The aim of this study was to analyze histological changes in the liver and to determine the role of Alanine Aminotransferase activity (ALT) and C-reactive protein (CRP) as biochemical markers of… Expand