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BACKGROUND Endothelial dysfunction can develop in the context of both obesity and obstructive sleep apnea (OSA) in children. However, the potential interactions between OSA and obesity have not been defined. METHODS Children who were prepubertal and nonhypertensive were recruited. Endothelial function was assessed in a morning fasted state, using a… (More)
BACKGROUND Endothelial dysfunction is a complication of both obesity and obstructive sleep apnea syndrome (OSAS), the latter being highly prevalent among obese children. It is unknown whether obesity causes endothelial dysfunction in children in the absence of OSAS. This study examines endothelial function in obese and non-obese children without OSAS. … (More)
Author's response to reviews: Please find enclosed the re-revised manuscript which addresses the point raised by the Reviewer 2 regarding the coefficient of variability of the endothelial function tests. This information is now included in the Methods Section. We look forward to the final acceptance of our manuscript.