Learn More
For the evaluation of non-palpable lesions of the breast, image-guided large-core needle biopsies are increasingly replacing needle-localized open breast biopsies. In this study, the diagnostic accuracy of this minimally invasive technique was evaluated by reviewing the available literature. Five cohort studies were included in a meta-analysis. Sensitivity(More)
OBJECTIVE Pelvic lymphadenectomy is considered the gold standard to diagnose and possibly treat lymphatic metastases in gynaecological cancer patients. The aim of this study is to evaluate whether all presurgical MRI detected lymph nodes were removed during the systematic pelvic lymph node dissection (PLND) in cervical cancer patients. METHODS 21(More)
Disease-specific mortality is the final outcome of a lung cancer screening trial, therefore cause of death verification is crucial. The use of death certificates for this purpose is debated because of bias, inaccurate completion and incorrect ante mortem diagnoses. A cause of death evaluation process was designed to ensure a uniform and unbiased(More)
Methods In the Dutch-Belgian randomized lung cancer screening trial (NELSON), the baseline CT screen result was based on the lung nodule with largest volume. According to the protocol, nodule volume<50mm3, 50-500mm3 and >500mm3 led to a negative, indeterminate and positive screen result, respectively. The protocol, however, allowed radiologists to manually(More)
Methods Baseline data of 2,240 solid intermediate-sized nodules (volume 50-500mm) in 1,498 Dutch-Belgian NELSON trial participants were used. Extrapolated volume based on semi-automatic (SA) maximum diameter and mean of maximum transversal and perpendicular diameter were compared to SA volume measurements by Bland-Altman plots. Analyses were repeated by(More)
Methods 197 solid lung cancers (192 participants) detected in all four screening rounds of the Dutch-Belgian randomized lung cancer screening trial (NELSON) were included. CTmorphological features included nodule shape, margin, location, volume, and volume-doubling time (VDT). Based on histopathology, cancers were divided into four groups: adenocarcinoma(More)
  • 1