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Isoechinulin-type alkaloids, variecolorins A-L, from halotolerant Aspergillus variecolor.
Twelve new compounds, variecolorins A-L ( 1- 12), together with eleven known analogues ( 13- 23) were isolated from the broth of a halotolerant fungus, Aspergillus variecolor. The structures ofExpand
Isolation, Structure Elucidation, and Antimycobacterial Properties of Dimeric Naphtho‐γ‐pyrones from the Marine‐Derived Fungus Aspergillus carbonarius
Two new dimeric naphtho‐γ‐pyrones, compounds 1 and 2, were isolated from the AcOEt extract of the fungal strain WZ‐4‐11 of Aspergillus carbonarius, together with eight known analogues, includingExpand
Aurantiomides A-C, quinazoline alkaloids from the sponge-derived fungus Penicillium aurantiogriseum SP0-19.
Three new quinazoline alkaloids, aurantiomides A (1), B (2), and C (3), along with the known metabolite anacine (4) were isolated from the sponge-derived fungus strain Penicillium aurantiogriseumExpand
Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17.
  • Y. Li, Chao Yu, +4 authors J. Li
  • Biology, Medicine
  • Molecular immunology
  • 30 September 2010
Triptolide is an active component of extracts derived from the medicinal vine Tripterygium Wilfordii Hook. f. (TWHF) whose extracts have been used to treat inflammatory bowel disease (IBD). We haveExpand
Three Novel, Structurally Unique Spirocyclic Alkaloids from the Halotolerant B‐17 Fungal Strain of Aspergillus variecolor
During our search for novel antitumor lead compounds from microorganisms living under extreme conditions, three novel alkaloids, variecolortides A–C (1–3), were isolated from the mycelia of theExpand
Four butenolides are novel cytotoxic compounds isolated from the marine-derived bacterium,Streptoverticillium luteoverticillatum 11014
Four known butenolides were isolated from the ethyl acetate extracts of the culture broth of the marine-derived bacterium,Streptoverticillum luteoverticillatum, by bioassay-guided fractionation. TheExpand
Trichodermamide A and aspergillazine A, two cytotoxic modified dipeptides from a marine-derived fungusSpicaria elegans
Two known modified dipeptides, trichodermamide A (1) and aspergillazine A (2), were isolated from an ethyl acetate extract of the metabolite of a marine-derived fungusSpicaria elegans, and were foundExpand
A new cytotoxic indole-3-ethenamide from the halotolerant fungus Aspergillus sclerotiorum PT06-1
A new cytotoxic indole-3-ethenamide (1) and two known compounds, 7-(3-methylbut-2-enyl)-1H-indole-3-carbaldehyde (2) and emodin (3) were isolated and identified from the ethyl acetate extract ofExpand
Citrinin dimers from the halotolerant fungus Penicillium citrinum B-57.
In order to search for structurally novel and bioactive natural compounds from microorganisms, a halotolerant fungal strain, Penicillium citrinum B-57, which mainly produces citrinin derivatives, wasExpand
DHA protects against experimental colitis in IL-10-deficient mice associated with the modulation of intestinal epithelial barrier function
A defect in the intestinal barrier is one of the characteristics of Crohn's disease (CD). The tight junction (TJ) changes and death of epithelial cells caused by intestinal inflammation play anExpand