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- Publications
- Influence
Screening for colorectal neoplasms with new fecal occult blood tests: update on performance characteristics.
- J. Allison, L. Sakoda, +10 authors J. Selby
- Medicine
- Journal of the National Cancer Institute
- 3 October 2007
BACKGROUND
One type of fecal occult blood test (FOBT), the unrehydrated guaiac fecal occult blood test (GT), is recommended by the United States Preventive Services Task Force and the Institute of… Expand
Association Between Time to Colonoscopy After a Positive Fecal Test Result and Risk of Colorectal Cancer and Cancer Stage at Diagnosis
Importance The fecal immunochemical test (FIT) is commonly used for colorectal cancer screening and positive test results require follow-up colonoscopy. However, follow-up intervals vary, which may… Expand
Variation of adenoma prevalence by age, sex, race, and colon location in a large population: implications for screening and quality programs.
- D. Corley, C. Jensen, +6 authors C. Quesenberry
- Medicine
- Clinical gastroenterology and hepatology : the…
- 1 February 2013
BACKGROUND & AIMS
Reliable community-based colorectal adenoma prevalence estimates are needed to inform colonoscopy quality standards and to estimate patient colorectal cancer risks; however, minimal… Expand
Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair
- F. Day, Katherine S Ruth, +238 authors A. Murray
- Medicine
- 1 December 2015
ABSTRACT: Menopause timing has a major impact on infertility and risk of disease. Younger age at natural (nonsurgical) menopause (ANM) is associated with a higher risk of osteoporosis, cardiovascular… Expand
Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis
- D. Saleheen, P. Haycock, +25 authors J. Danesh
- Medicine
- The lancet. Diabetes & endocrinology
- 1 July 2017
Summary Background The lipoprotein(a) pathway is a causal factor in coronary heart disease. We used a genetic approach to distinguish the relevance of two distinct components of this pathway,… Expand
Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community-based study
- Chyke A Doubeni, D. Corley, +12 authors R. Fletcher
- Medicine
- Gut
- 12 October 2016
Objective Screening colonoscopy's effectiveness in reducing colorectal cancer mortality risk in community populations is unclear, particularly for right-colon cancers, leading to recommendations… Expand
Fecal Immunochemical Test Program Performance Over 4 Rounds of Annual Screening
- C. Jensen, D. Corley, +13 authors P. Mysliwiec
- Medicine
- Annals of Internal Medicine
- 26 January 2016
Context The fecal immunochemical test is an effective way to screen for colorectal cancer, but we know more about how well it does the first time it is used and less about how well it does in later… Expand
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells
- K. Gong, W. Zhao, +7 authors Jesus A. Araujo
- Biology, Medicine
- Genome Biology
- 26 July 2007
BackgroundAmbient air pollution is associated with increased cardiovascular morbidity and mortality. We have found that exposure to ambient ultrafine particulate matter, highly enriched in redox… Expand
Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study
- S. Ahmad, W. Zhao, +16 authors D. Saleheen
- Medicine
- BMC Medical Genetics
- 18 December 2015
BackgroundMultiple genetic variants have been reliably associated with obesity-related traits in Europeans, but little is known about their associations and interactions with lifestyle factors in… Expand
Citalopram provides little or no benefit in nondepressed patients with irritable bowel syndrome.
- U. Ladabaum, A. Sharabidze, +6 authors Craig Pepin
- Medicine
- Clinical gastroenterology and hepatology : the…
- 2010
BACKGROUND & AIMS
Data on the benefit of selective serotonin reuptake inhibitors (SSRIs) in irritable bowel syndrome (IBS) are conflicting. The longitudinal relationship between clinical symptoms and… Expand