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- Publications
- Influence
Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro.
- W. Zhang, H. Chen, Chuan Zhang, Run-hui Liu, H. Li, H. Chen
- Medicine
- Planta medica
- 2006
Astragaloside IV is the major active constituent of Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases in China. However, the effects of astragaloside IV… Expand
Network Pharmacology in Traditional Chinese Medicine
- S. Li, Tai-Ping Fan, Wei Jia, A. Lu, W. Zhang
- Medicine
- Evidence-based complementary and alternative…
- 24 February 2014
Network pharmacology is becoming a cutting-edge research field in current drug discovery and drug development thanks to rapid progress in systems biology, network biology, and chemical biology. By… Expand
NFAT as cancer target: mission possible?
- Jiang-jiang Qin, S. Nag, +4 authors R. Zhang
- Biology, Medicine
- Biochimica et biophysica acta
- 1 December 2014
The NFAT signaling pathway regulates various aspects of cellular functions; NFAT acts as a calcium sensor, integrating calcium signaling with other pathways involved in development and growth, immune… Expand
Regulation of egg quality and lipids metabolism by Zinc Oxide Nanoparticles.
- Y. Zhao, L. Li, +7 authors Zhi-Hui Hao
- Chemistry, Medicine
- Poultry science
- 1 April 2016
This investigation was designed to explore the effects of Zinc Oxide Nanoparticles (ZnO NP) on egg quality and the mechanism of decreasing of yolk lipids. Different concentration of ZnO NP and ZnSO4… Expand
Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang.
ETHNOPHARMACOLOGICAL RELEVANCE
Huang-Lian-Jie-Du-Tang (HLJDT oren-gedoku-to in Japanese), a classical traditional Chinese medicine (TCM) formula, is well known for the treatment of… Expand
Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways
A number of emerging studies suggest that air pollutants such as hydrogen sulfide (H2S) and ammonia (NH3) may cause a decline in spermatozoa motility. The impact and underlying mechanisms are… Expand
Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
- Guozhen Wu, L. Zhu, +9 authors W. Zhang
- Biology, Medicine
- Antioxidants & redox signaling
- 10 October 2017
AIMS
Oxidative stress is considered the major cause of tissue injury after cerebral ischemia. The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is one of the most important defensive… Expand
Protective Effects of Huang-Lian-Jie-Du-Tang against Polymicrobial Sepsis Induced by Cecal Ligation and Puncture in Rats
- Yufen Wei, L. Shan, Liming Qiao, Run-hui Liu, Z. Hu, W. Zhang
- Medicine
- Evidence-based complementary and alternative…
- 2 December 2013
Huang-Lian-Jie-Du-Tang (HLJDT) is a traditional formula that has long been used for treatment of inflammatory diseases in Traditional Chinese Medicine. In this study, we examined its protective… Expand
Chemical Constituents of Plants from the Genus Dracocephalum
- Q. Zeng, Hui-zi Jin, +6 authors W. Zhang
- Chemistry, Medicine
- Chemistry & biodiversity
- 1 August 2010
The gene expression profiles in response to 102 traditional Chinese medicine (TCM) components: a general template for research on TCMs
- C. Lv, Xueting Wu, +8 authors W. Zhang
- Medicine
- Scientific Reports
- 23 March 2017
Traditional Chinese medicines (TCMs) have important therapeutic value in long-term clinical practice. However, because TCMs contain diverse ingredients and have complex effects on the human body, the… Expand