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Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein.
Virus-infected mammalian cells are a battleground: cells mount antiviral defenses against the virus, and these defenses are countered by the infecting virus. The eventual outcome of this war is a… Expand
Cryphonectria hypovirus 3, a virus species in the family hypoviridae with a single open reading frame.
- C. Smart, W. Yuan, R. Foglia, D. Nuss, D. Fulbright, B. Hillman
- Biology, Medicine
- 5 December 1999
Isolate Grand Haven (GH) 2 is a naturally occurring isolate of the chestnut blight fungus, Cryphonectria parasitica, that is greatly reduced in virulence due to the presence of a double-stranded RNA… Expand
Crucial role of CA cleavage sites in the cap‐snatching mechanism for initiating viral mRNA synthesis
In viral cap‐snatching, the endonuclease intrinsic to the viral polymerase cleaves cellular capped RNAs to generate capped fragments that are primers for viral mRNA synthesis. Here we demonstrate… Expand
Cytoplasmic trafficking of the canine parvovirus capsid and its role in infection and nuclear transport.
To begin a successful infection, viruses must first cross the host cell plasma membrane, either by direct fusion with the membrane or by receptor-mediated endocytosis. After release into the… Expand
Nonstructural protein-2 and the replication of canine parvovirus.
The nonstructural protein-2 (NS2) of canine parvovirus (CPV) is produced from the left-hand open reading frame of the viral genome and contains 87 amino-terminal amino acids in common with… Expand
Satellite and defective RNAs of Cryphonectria hypovirus 3-grand haven 2, a virus species in the family Hypoviridae with a single open reading frame.
Cryphonectria parasitica hypovirus 3-Grand Haven 2 (CHV3-GH2) is the most recently characterized member of the Hypoviridae family of viruses associated with hypovirulence of the chestnut blight… Expand
Herpes Simplex Virus 1 US3 Phosphorylates Cellular KIF3A To Downregulate CD1d Expression
- R. Xiong, Ping Rao, Seil Kim, M. Li, X. Wen, W. Yuan
- Biology, Medicine
- Journal of Virology
- 15 April 2015
ABSTRACT Herpes simplex virus 1 (HSV-1) causes one of the most prevalent herpesviral infections in humans and is the leading etiological agent of viral encephalitis and eye infections. Our… Expand
Canine parvovirus capsid assembly and differences in mammalian and insect cells.
We examined the assembly processes of the capsid proteins of canine parvovirus (CPV) in mammalian and insect cells. In CPV-infected cells empty capsids assembled within 15 min, and then continued to… Expand
Comparison of two single-chain antibodies that neutralize canine parvovirus: analysis of an antibody-combining site and mechanisms of neutralization.
We cloned the heavy- and light-chain variable domains of two monoclonal antibodies that recognize each of the two major neutralizing antigenic sites of the canine parvovirus (CPV) capsid. After… Expand
In vitro translational analysis of genomic, defective, and satellite RNAs of Cryphonectria hypovirus 3-GH2.
Cryphonectria hypovirus 3-GH2 (CHV3-GH2) is a member of the fungal virus family Hypoviridae that differs from previously characterized members in having a single large open reading frame with the… Expand