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Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits.
Bioassay-guided isolation and purification of the ethyl acetate extract of Moringa oleifera fruits yielded three new phenolic glycosides that are reported to have potent NO-inhibitory activity and reduced LPS-mediated iNOS expression.
Post‐translational Modification in Microviridin Biosynthesis
It is shown that a prepeptide undergoes post‐translational modification through cross‐linking by ester and amide bond formation by the RimK homologues MvdD and MvdC, respectively and suggests the potential for widespread occurrence of microviridin‐like compounds in a broad range of bacteria.
Isolation and structure determination of two microcystins and sequence comparison of the McyABC adenylation domains in Planktothrix species.
Two homotyrosine (Hty)-containing microcystin variants are reported, which were isolated from strain No80 of Planktothrix rubescens and elucidated using amino acid analysis as well as 1D and 2D NMR techniques.
Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula.
Apratoxin A (1), a potent cytotoxin with a novel skeleton, has been isolated from the marine cyanobacterium Lyngbya majuscula Harvey ex Gomont; however, it was only marginally active in vivo against a colon tumor and ineffective against a mammary tumor.
Isolation, structure determination, and biological activity of Lyngbyabellin A from the marine cyanobacterium lyngbya majuscula.
The isolation of 1 from L. majuscula once more supports the proposal that many compounds originally isolated from the sea hare Dolabella auricularia are of cyanobacterial origin and was shown to be a potent disrupter of the cellular microfilament network.
Ecological roles for water-borne metabolites from Antarctic soft corals
The organic fraction of seawater collected near this soft coral showed potent antibacterial activity, andctions support the release of waterborne allelochemicals by these 2 species.