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Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages.
  • S. Heo, W. Yoon, +7 authors Y. Jeon
  • Biology, Medicine
  • Food and chemical toxicology : an international…
  • 1 August 2010
Results suggest that the use of fucoxanthin may be a useful therapeutic approach for the various inflammatory diseases. Expand
Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, and pro-inflammatory cytokines in RAW 264.7 macrophages.
D-limonene is an effective inhibitor of lipopolysaccharide (LPS)-induced NO and prostaglandin E(2) production in RAW 264.7 macrophages and may be considered a potential anti-inflammatory candidate, according to the results. Expand
Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages.
It is demonstrated that FX reduces the levels of pro-inflammatory mediators including NO, PGE₂, IL-1β, TNF-α, and IL-6 via the inhibition of NF-κB activation and the suppression of MAPK phosphorylation in RAW 264.7 cells. Expand
Suppression of pro-inflammatory cytokines, iNOS, and COX-2 expression by brown algae Sargassum micracanthum in RAW 264.7 macrophages
It is suggested that S. micracanthum extracts may be considered potential anti-inflammatory candidates for topical application and performed MTT assays on human dermal fibroblast cells, as well as primary skin irritation tests, and did not induce any adverse reactions. Expand
Antioxidative and antimicrobial activities of Sargassum muticum extracts
The solvent extracts of Sargassum muticum, which were extracted by using several solvents with different polarities, were prepared for use as natural preservatives. The S. muticum extract with 80%Expand
In vitro anti-inflammatory and anti-oxidative effects of Cinnamomum camphora extracts.
Data suggest that the anti-inflammatory actions of Cinnamomum camphora may be due to the modulation of cytokine, NO and PGE(2) production and oxidative stress, and of the subfractions tested, the EtOAc extract may be further studied to isolate the active anti- inflammatory principles. Expand
Complete mitochondrial genome of the rock bream Oplegnathus fasciatus (Perciformes, Oplegnathidae) with phylogenetic considerations.
The complete nucleotide sequence of the mitochondrial genome for the rock bream, Oplegnathus fasciatus, was determined and a termination-associated sequence and a conserved sequence block characteristic to this region were identified. Expand
Anti-inflammatory effect of fucoxanthin derivatives isolated from Sargassum siliquastrum in lipopolysaccharide-stimulated RAW 264.7 macrophage.
Findings indicate that the anti-inflammatory properties of FXA may be due to the inhibition of iNOS/NO pathway which associated with the attenuation of TNF-α and IL-6 formation, and may provide a potential therapeutic approach for inflammation related diseases. Expand
Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E2, and proinflammatory cytokines in RAW264.7 macrophages.
The pharmacological and biological effects of Oenothera laciniata extracts on the production of inflammatory mediators in macrophages were elucidated and it was suggested that O. laciniATA extracts be considered possible anti-inflammatory candidates for topical application. Expand
Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate
The results suggest that LJFE can be used as a potential anti-osteoarthritic agent and reduce the expression of inflammatory cytokines in OA by using a rat model of monosodium iodoacetate-induced OA. Expand