Author pages are created from data sourced from our academic publisher partnerships and public sources.
Allele-specific Holliday junction formation: a new mechanism of allelic discrimination for SNP scoring.
- Qinghong Yang, A. Lishanski, W. Yang, S. Hatcher, Henrietta Seet, J. Gregg
- Biology, Medicine
- Genome research
- 1 July 2003
We report here a new mechanism for allelic discrimination--allele-specific Holliday Junction formation. The Holliday Junction (HJ) is a unique DNA structure that can be formed in a… Expand
Denicotinized versus average nicotine tobacco cigarette smoking differentially releases striatal dopamine.
- E. Domino, L. Ni, +6 authors J. Zubieta
- Psychology, Medicine
- Nicotine & tobacco research : official journal of…
INTRODUCTION Nicotine has long been recognized as a necessary but insufficient component of tobacco cigarettes to maintain a psychophysiological need to smoke. This study examined venous plasma… Expand
Homozygous Deletion of Six Olfactory Receptor Genes in a Subset of Individuals with Beta-Thalassemia
Progress in the functional studies of human olfactory receptors has been largely hampered by the lack of a reliable experimental model system. Although transgenic approaches in mice could… Expand
Petrographic Features of Kerogen in Gas Shales and their Effect on Hydrocarbon Storage
Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease.
BACKGROUND Huntington's disease (HD) is a neurological disorder caused by mutations in the huntingtin (HTT) gene, the product of which leads to selective and progressive neuronal cell death in the… Expand
Analysis of mannitol in pharmaceutical formulations using hydrophilic interaction liquid chromatography with evaporative light-scattering detection.
This study demonstrates the use of hydrophilic interaction liquid chromatography (HILIC) for the separation of both active and inactive ingredients in pharmaceuticals from a single injection.… Expand
Detecting the C282Y and H63D mutations of the HFE gene by Holliday Junction-based allele-specific genotyping methods.
Hereditary hemochromatosis, one of the most common genetic diseases in Caucasians, is characterized by excessive iron deposition secondary to hyperabsorption of dietary iron and can potentially can… Expand
Prognostic Significance of Genomic Alterations in Mantle Cell Lymphoma
Background Whole genome, whole exome, and targeted sequencing have identified various genomic alterations in mantle cell lymphoma (MCL). There remains limited data correlating genomic alterations… Expand
A Comparison Study of Buxiban Learning in Hong Kong and Taiwan
The study aimed to explore students’ perspective and reasons for going to a Buxiban, and whether their English ability improved after attending a Buxiban. Buxibans, also known as cram schools,… Expand
Relationship between the Computed Tomography - Measured Initial Primary Tumor Volume, Urine VMA Level and Stage in Neuroblastoma Patients
Background: Nowadays, volumetric data acquisition has allowed for the accurate quantification of volumetric tumor burden. However, few studies have focused on the relationship between neuroblastoma… Expand