• Publications
  • Influence
Induction of miR‐29a by saturated fatty acids impairs insulin signaling and glucose uptake through translational repression of IRS‐1 in myocytes
MicroRNAs have been shown to play an important role in insulin signaling but their biological function in insulin resistance induced by saturated fatty acids (SFA) remains largely unknown. Here, weExpand
  • 63
  • 6
A Study on Greenhouse Automatic Control System Based on Wireless Sensor Network
The system proposed in this paper collects temperature of leaves and humidity on leaves of crop. Expand
  • 105
  • 4
Saturated fatty acid‐induced miR‐195 impairs insulin signaling and glycogen metabolism in HepG2 cells
MicroRNAs (miRNAs) play an important role in insulin signaling and insulin secretion, but the role of miRNAs in the association between obesity and hepatic insulin resistance is largely unknown. ThisExpand
  • 37
  • 4
  • PDF
Obesity-induced miR-15b is linked causally to the development of insulin resistance through the repression of the insulin receptor in hepatocytes.
SCOPE Obesity increases intracellular lipid accumulation in key tissues or organs, which often leads to metabolic dysfunction and insulin resistance. Diets rich in saturated fatty acid (SFA)Expand
  • 32
  • 2
Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1
Obesity is defined as the excessive accumulation of body fat that ultimately leads to chronic metabolic diseases. Diets rich in saturated fatty acids (SFA) exacerbate obesity and hepatic steatosis,Expand
  • 28
  • 2
  • PDF
CTRP5 ameliorates palmitate-induced apoptosis and insulin resistance through activation of AMPK and fatty acid oxidation.
  • W. Yang, W. Lee
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 26 September 2014
Lipotoxicity resulting from a high concentration of saturated fatty acids is closely linked to development of insulin resistance, as well as apoptosis in skeletal muscle. CTRP5, an adiponectinExpand
  • 20
  • 2
The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational repression of IRS-1 in SK-Hep1 cells.
MicroRNA (miRNA) is a class of endogenous small noncoding RNA that negatively regulates gene expression at the post-transcriptional level and plays an important role in the pathogenesis of variousExpand
  • 23
  • 1
Saturated fatty acids-induced miR-424-5p aggravates insulin resistance via targeting insulin receptor in hepatocytes.
The excessive intake of saturated fatty acids (SFA) causes obesity and liver steatosis, which are major risk factors for insulin resistance and type 2 diabetes. Although the expression of certainExpand
  • 9
  • 1
Implications of microRNAs in the pathogenesis of diabetes
Diabetes is a complex metabolic disease with an etiology that includes genetic, epigenetic and environmental factors that lead to several different defects of glucose homeostasis, primarily in theExpand
  • 34
MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells.
Dietary saturated fatty acids (SFA) in excess not only induce hepatic insulin resistance, but also result in type 2 diabetes (T2DM). Although microRNAs (miRNAs) participate widely in the pathogenesisExpand
  • 17