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A Peripheral Blood Diagnostic Test for Acute Rejection in Renal Transplantation
TLDR
The 5‐gene set can diagnose acute rejection (AR) potentially avoiding the need for invasive renal biopsy, and data support the conduct of a prospective study to validate the clinical predictive utility of this diagnostic tool. Expand
Paeonol Attenuates Advanced Oxidation Protein Product-Induced Oxidative Stress Injury in THP-1 Macrophages
TLDR
Results indicate that paeonol can decrease proinflammatory cytokines in THP-1 macrophages, likely through RAGE, CD36, SR-A, and SR-B1-mediated signals involving NADPH oxidase-dependent ROS generation, and suggests that paelol can be used as a therapeutic agent for diseases contributing to oxidative stress injury. Expand
Regulatory T cells protect against hypoxia-induced pulmonary arterial hypertension in mice.
TLDR
The results indicated that Tregs protected against hypoxia‑induced PAH in mice; the mechanisms of which may proceed via the suppression of the inflammatory response, as T Regs were found to enhance anti‑inflammatory cytokine levels, inhibit HPASMCs proliferation and regulate the cell cycle. Expand
Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome.
TLDR
Overall, the present study has discovered that SK0506 can reverse several components of the metabolic syndrome primarily through acting on hyperlipidaemia and visceral obesity. Expand
Managing the Combination of Nonalcoholic Fatty Liver Disease and Metabolic Syndrome with Chinese Herbal Extracts in High-Fat-Diet Fed Rats
  • Yi Tan, Weiguo Lao, +5 authors X. Qu
  • Medicine
  • Evidence-based complementary and alternative…
  • 18 February 2013
TLDR
It is discovered that SGE is capable of managing metabolic and histological abnormalities of NAFLD and MetS and may be an optimal treatment for the combination of NA FLD andMetS. Expand
Beneficial effects of the Chinese herbal medicine Sanjie Zhentong Capsule on experimental endometriosis in rats.
TLDR
Results indicate that SJZTC and its two main components are effective in reducing the development of endometriosis. Expand
Protective effects of Sapindus mukorossi Gaertn against fatty liver disease induced by high fat diet in rats.
TLDR
Alcohol extracts of S.mukorossi Gaertn can regulate the level of blood fat and improve the pathological changes of the hepatic tissues in NAFLD-rat model, which demonstrates the effects of down-regulating fat level and protecting liver. Expand
HLA-G expression in the peripheral blood of live kidney transplant recipients.
BACKGROUND The human leukocyte antigen-G (HLA-G) has been considered to be an important tolerogeneic molecule playing an essential role in maternal-fetal tolerance, upregulated in the context ofExpand
Anti-inflammatory effects of Reduning Injection (热毒宁注射液) on lipopolysaccharide-induced acute lung injury of rats
TLDR
Anti-inflammatory effects of RDN was demonstrated to be preventing pulmonary neutrophil infiltration, lowering MPO activity, TNF-α and iNOS gene expression by inhibiting NF-κB activity in LPS-induced ALI. Expand
ReDuNing, a patented Chinese medicine, reduces the susceptibility to H1N1 influenza of mice loaded with restraint stress
TLDR
Preliminary support is provided to suggest that RDN can reduce the susceptibility to, and the severity of influenza in restraint-stressed mice, and its impact as potential anti-influenza treatments which rebalances homeostasis in the body caused by stress. Expand
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