• Publications
  • Influence
Human chorionic gonadotropin β induces cell motility via ERK1/2 and MMP-2 activation in human glioblastoma U87MG cells
It is demonstrated that hCGβ phosphorylated ERK1/2 upregulating MMP-2 expression and activity leading to cell migration and invasion, suggesting that h CGβ, ERK 1/2 and M MP-2 are the potential targets to inhibit glioblastoma invasion.
[16S rRNA gene sequencing for pathogen identification from clinical specimens].
By improving the extract DNA method, selecting suitable primer, developing the gene amplification and sequencing procedure, direct 16S rRNA gene sequencing can identify the pathogens from clinical specimens.
Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry in the screening of vanA-positive Enterococcus faecium.
MALDI-TOF MS can be used as a screening test for discrimination between vanA-positive E. faecium andVanA-negative E. Faecium in screening vancomycin-resistant Enterococcus faecius.
Multiple human prolactin receptors and signaling
It is discovered that a mimic of phosphorylated prolactin induced p21 waf1 expression via a short form of PRLR S1b in prostate cancer cells, suggesting that shorter PRLR might modulate long PRLR function via multiple PRLR system in both mRNA and protein levels.
Control of avian influenza A H5N1 in China.
  • W. Wu
  • Medicine
    The Lancet. Infectious diseases
  • 1 August 2009
An outbreak of Burkholderia stabilis colonization in a nasal ward.
A mimic of phosphorylated prolactin induces apoptosis by activating AP-1 and upregulating p21/waf1 in human prostate cancer PC3 cells.
It is demonstrated that S179D PRL activates JNK and AP-1, which leads to p21 upregulation and apoptosis in human prostate PC3 cancer cells.
[Application of molecular method in identification of bacterial endophthalmitis].
Molecular identification method is a rapid and efficient approach for the diagnosis of bacterial infective endophthalmitis and other infectious diseases.