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Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.
BACKGROUND The antiplatelet effect of aspirin is attributed to platelet cyclooxygenase-1 inhibition. Controversy exists on the prevalence of platelet resistance to aspirin in patients with coronaryExpand
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Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation*
Background: Secreted PCSK9 regulates LDL levels in plasma by mediating degradation of hepatic LDL receptors. Results: LDL binds to PCSK9 in human plasma and in vitro and inhibits PCSK9 binding toExpand
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Tsunami-generating rock fall and landslide on the south coast of Nuussuaq, central West Greenland
During the afternoon of 21 November 2000 the village of Saqqaq in central West Greenland was hit by a series of giant waves. Ten small boats were destroyed, but luckily neither humans nor dogs wereExpand
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A new seamless digital 1:500 000 scale geological map of Greenland
For around 40 years, the Geological Survey of Greenland (GGU) and later the Geological Survey of Denmark and Greenland (GEUS) conducted systematic geological overview mapping of Greenland, leading toExpand
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Geological assessment of the East Greenland margin
The East Greenland margin consists of a number of sedimentary basins, platforms and structural highs (Figs 1, 2). Due to the challenges imposed by the Arctic climate, the region is in an early stageExpand
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Myeloid-Derived Suppressor Cell (MDSC) Dynamics In FVIII-Exposed Hemophilia A Mice: Novel Therapeutic Implications
Introduction Among FVIII-treated hemophilia A (HA) patients, 25-30% develop FVIII antibodies that inhibit its pro-coagulant function. However, the etiology of FVIII inhibitor formation remains poorlyExpand
Atrial Arrhythmias in Clinically Manifest Cardiac Sarcoidosis: Incidence, Burden, Predictors, and Outcomes
Background Recent data have suggested a substantial incidence of atrial arrhythmias (AAs) in cardiac sarcoidosis (CS). Our study aims were to first assess how often AAs are the presenting feature ofExpand