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A new class of membrane-bound chemokine with a CX3C motif
TLDR
The structure, biochemical features, tissue distribution and chromosomal localization of CX3C chemokine all indicate that it represents a unique class of chemokines that may constitute part of the molecular control of leukocyte traffic at the endothelium. Expand
STING: A Statistical Information Grid Approach to Spatial Data Mining
TLDR
The idea is to capture statistical information associated with spatial cells in such a manner that whole classes of queries and clustering problems can be answered without recourse to the individual objects. Expand
Efficient mining of frequent subgraphs in the presence of isomorphism
TLDR
This work proposes a novel frequent subgraph mining algorithm: FFSM, which employs a vertical search scheme within an algebraic graph framework it has developed to reduce the number of redundant candidates proposed. Expand
High-performance neuroprosthetic control by an individual with tetraplegia
TLDR
With continued development of neuroprosthetic limbs, individuals with long-term paralysis could recover the natural and intuitive command signals for hand placement, orientation, and reaching, allowing them to perform activities of daily living. Expand
The diploid genome sequence of an Asian individual
TLDR
Genotyping analysis showed that SNP identification had high accuracy and consistency, indicating the high sequence quality of this assembly, and the potential usefulness of next-generation sequencing technologies for personal genomics. Expand
Ranking Outliers Using Symmetric Neighborhood Relationship
TLDR
A simple but effective measure on local outliers based on a symmetric neighborhood relationship that considers both neighbors and reverse neighbors of an object when estimating its density distribution and shows that it is more effective in ranking outliers. Expand
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
TLDR
It is shown that the individual PB insertions can be removed from established iPS cell lines, providing an invaluable tool for discovery, and the traceless removal of reprogramming factors joined with viral 2A sequences delivered by a single transposon from murine iPS lines is demonstrated. Expand
The DNA methylation landscape of human early embryos
TLDR
Insight is provided into the critical features of the methylome of human early embryos, as well as its functional relation to the regulation of gene expression and the repression of transposable elements, which indicate that early embryos tend to retain higher residual methylation at the evolutionarily younger and more active transposability elements. Expand
The Dog Genome: Survey Sequencing and Comparative Analysis
TLDR
A survey of the dog genome sequence demonstrates the power of sample sequencing for comparative analysis of mammalian genomes and the generation of species-specific resources. Expand
Enhanced biclustering on expression data
TLDR
The model of bicluster is generalized to incorporate null values and a probabilistic algorithm (FLOC) is proposed that can discover a set of k possibly overlapping biclusters simultaneously and can be extended to support additional features that suit different requirements at virtually little cost. Expand
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