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THE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY
A survey has been conducted in Whickham, County Durham, to determine the prevalence of thyroid disorders in the community. Two thousand seven hundred and seventy‐nine people (82.4% of the availableExpand
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Epidemiology and prevention of clinical and subclinical hypothyroidism.
Iodine deficiency is the most common cause of hypothyroidism worldwide. In persons living in iodine-replete areas, causes are congenital, spontaneous because of chronic autoimmune disease (atrophicExpand
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The development of ischemic heart disease in relation to autoimmune thyroid disease in a 20-year follow-up study of an English community.
The original Whickham Survey documented risk factors for cardiovascular disease and the prevalence of thyroid disorders in a sample of 2779 adults that closely matched the British population. AExpand
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LIPID PROFILES AND CARDIOVASCULAR DISEASE IN THE WHICKHAM AREA WITH PARTICULAR REFERENCE TO THYROID FAILURE
The age and sex distribution of ischaemic heart disease (IHD), other vascular disorders and serum lipid concentrations and the possible association between these factors and thyroid failure have beenExpand
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Natural history of autoimmune thyroiditis.
One hundred and sixty-three asymptomatic people with thyroid antibodies or raised serum thyrotrophin (TSH) concentrations, or both, and 209 age-matched and sex-matched controls without either markerExpand
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Growth Hormone Release Inhibiting Hormone in Acromegaly
Growth hormone release inhibiting hormone (GHRIH) was administered by constant infusion over 75 minutes to eight acromegalic patients at different doses. 100 to 1,000 μg were equally effective inExpand
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Population screening for autoimmune thyroid disease.
Whether or not healthy adults in the community would benefit from screening for autoimmune thyroid disease is controversial. Although the prevalence of unsuspected overt thyroid disease is low, aExpand
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Renal replacement treatment for diabetic patients in Newcastle upon Tyne and the Northern region, 1964-88.
OBJECTIVES--To review the experience of renal replacement treatment in diabetic patients treated in Newcastle upon Tyne and the Northern region from 1964 to 1988, and to compare the morbidity andExpand
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Action of growth-hormone-release inhibitory hormone in healthy men and in acromegaly.
Abstract The synthetic growth-hormone-release inhibitory hormone (G.R.-I.H.) inhibits G.H. response to insulin-induced hypoglycaemia without affecting the prolactin or corticosteroid responses, butExpand
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FACTORS CONTRIBUTING TO DEATHS OF DIABETICS UNDER FIFTY YEARS OF AGE
Abstract Factors contributing to the deaths of 448 diabetics under the age of fifty years who died in the United Kingdom in 1979 are examined. Two- thirds died during the fifth decade of life. TheExpand
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