• Publications
  • Influence
Aripiprazole Attenuates the Discriminative-Stimulus and Subject-Rated Effects of D-Amphetamine in Humans
The results of animal research suggest that the use of partial agonists at dopamine (DA) D2 receptors may be an effective strategy for the treatment of stimulant dependence. Aripiprazole is anExpand
  • 77
  • 12
The reinforcing, subject-rated, performance, and cardiovascular effects of d-amphetamine: influence of sensation-seeking status.
Individual differences that may contribute to vulnerability to abuse drugs have been identified. Sensation-seeking status has been shown to influence both vulnerability to drug use and response toExpand
  • 73
  • 8
A retrospective claims analysis of combination therapy in the treatment of adult attention-deficit/hyperactivity disorder (ADHD)
BackgroundCombination therapy in managing psychiatric disorders is not uncommon. While combination therapy has been documented for depression and schizophrenia, little is known about combinationExpand
  • 30
  • 7
Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: abuse potential and relative potencies
RationaleNonmedical use and abuse of prescription opioids is an increasing public health problem. Intravenous (IV) administration of opioid analgesics intended for oral use is not uncommon; yet,Expand
  • 63
  • 6
A low dose of aripiprazole attenuates the subject-rated effects of d-amphetamine.
Despite increased reports of amphetamine abuse and dependence, a putative pharmacotherapy has yet to be identified. In a previous study from our laboratory, 20 mg aripiprazole, an atypicalExpand
  • 52
  • 5
Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration
RationaleThe reinforcing effects of stimulant drugs are modulated by behavioral demands following drug administration.ObjectiveThe objective of this study was to assess the reinforcing effects ofExpand
  • 84
  • 4
Methylphenidate increases cigarette smoking in participants with ADHD
RationaleMethylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest thatExpand
  • 33
  • 4
Risperidone Attenuates the Discriminative-Stimulus Effects of d-Amphetamine in Humans
Studies conducted with nonhuman laboratory animals have consistently shown that atypical antipsychotics that are mixed dopamine and serotonin antagonists attenuate the discriminative-stimulus effectsExpand
  • 81
  • 3
Cocaine Choice in Humans During d-Amphetamine Maintenance
The results of preclinical laboratory experiments and clinical trials indicate that agonist replacements such as d-amphetamine may be a viable option for managing cocaine dependence. This studyExpand
  • 60
  • 3
Reinforcing, subject-rated, performance and physiological effects of methylphenidate and d-amphetamine in stimulant abusing humans
Methylphenidate has potential for abuse because it produces behavioural effects similar to those observed with other abused stimulants, such as d-amphetamine and cocaine. The aim of this study was toExpand
  • 65
  • 3