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Water proton MR properties of human blood at 1.5 Tesla: Magnetic susceptibility, T1, T2, T  *2 , and non‐Lorentzian signal behavior
Determinations of the relaxation parameters of blood are reported, employing in vitro samples that are well representative of human blood in situ, and the Gaussian component, AR*, should be recognized in accurate modeling of MRI phenomena that depend upon the magnetic state of blood. Expand
Pitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice.
The morphological data suggest that PITX1 haploinsufficiency may cause a developmental field defect preferentially affecting the lateral lower leg, a theory that accounts for similar findings in human clubfoot. Expand
A novel technology for the imaging of acidic prostate tumors by positron emission tomography.
A novel class of noninvasive pH-selective positron emission tomography imaging agents is introduced and opens new research directions in the diagnosis of acidic solid tumors. Expand
Hemoglobin concentration and erythrocyte cation content.
The increase in the concentration of cations in these anemic erythrocytes was of roughly the magnitude to be expected as a result of the decrease in the osmotic coefficient of hemoglobin with the fall in ery Throcyte hemoglobin concentration. Expand
Bioresorbable pressure sensors protected with thermally grown silicon dioxide for the monitoring of chronic diseases and healing processes
These findings establish routes for the design and fabrication of bioresorbable pressure monitors that meet requirements for clinical use and demonstrate measurement accuracies that compare favourably to those of the most sophisticated clinical standards for non-resorbable devices by monitoring intracranial pressures in rats for 25 days. Expand
Metabolic response of the CWR22 prostate tumor xenograft after 20 Gy of radiation studied by 1H spectroscopic imaging.
Nuclear magnetic resonance spectroscopy provided a method with which to monitor metabolic changes of tumor response to XRT that preceded and predicted PSA and tumor volume changes. Expand
A Transition Program for Underprepared Students in General Chemistry: Diagnosis, Implementation, and Evaluation
We developed an online exam to diagnose students who are underprepared for college-level general chemistry and implemented a program to support them during the general chemistry sequence. ThisExpand
Imaging Intratumoral Convection: Pressure-Dependent Enhancement in Chemotherapeutic Delivery to Solid Tumors
Data indicate that the modulation of convective flow within tumors can improve the delivery of (LMW) chemotherapeutics and show the potential role for noninvasive imaging of this process in vivo. Expand
The NMR chemical shift pH measurement revisited: Analysis of error and modeling of a pH dependent reference
To extend the useful pH range and utility of NMR pH determination methodology, a more general model is developed in which the internal reference species is also considered as having a pH‐dependent chemical shift. Expand
White-matter diffusion fMRI of mouse optic nerve
The experimental results strongly suggest that osmotic after-effects of nerve impulses through the axonal fibers are responsible for the observed ADC decrease. Expand