W. Sibbald

Publications367
h-index67
Citations35,630
Highly Influential Citations1,031
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Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of…
TLDR
Broad definitions of sepsis and the systemic inflammatory response syndrome were proposed, along with detailed physiologic parameters by which a patient may be categorized, and the use of severity scoring methods when dealing with septic patients was recommended as an adjunctive tool to assess mortality. Expand
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of…
An American College ofChest Physicians/Society ofCritical Care Medicine Consensus Conference was held in Northbrook in August 1991 with the goal of agreeing on a set of de6nitions that could be… Expand
Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome.
TLDR
This multiple organ dysfunction score, constructed using simple physiologic measures of dysfunction in six organ systems, mirrors organ dysfunction as the intensivist sees it and correlates strongly with the ultimate risk of ICU mortality and hospital mortality. Expand
The ACCP-SCCM consensus conference on sepsis and organ failure.
TLDR
Only recently has the knowledge of the molecular and cellular events that occur in sepsis and its sequelae begun to shed light on the complex cascade of events underlying these disorders. Expand
Peripheral nerve function in sepsis and multiple organ failure.
TLDR
The results were consistent with the polyneuropathy being due to the same mechanisms that are currently postulated to cause dysfunction in this syndrome of other organ systems (including the neuromuscular respiratory system). Expand
An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses.
TLDR
This paper discusses the decision-making process for withdrawing mechanical Ventilation in palliative care and some of the management techniques used in this process. Expand
Effect of stored-blood transfusion on oxygen delivery in patients with sepsis.
TLDR
It is postulate that the poorly deformable transfused red blood cells cause micro-circulatory occlusion in some organs, which may lead to tissue ischemia inSome organs. Expand
Polyneuropathy in critically ill patients.
TLDR
The electrophysiological and morphological features indicate a primary axonal polyneuropathy with sparing of the central nervous system, which allow diagnosis during life, and encourage continued intensive management since recovery from the polyne neuropathy may occur. Expand
Development of medical checklists for improved quality of patient care.
TLDR
A narrative review of the literature was conducted to outline the methodology to designing and implementing clear and effective medical checklists, suggesting a highly effective, standardized methodology for the development and design of medical-specific checklists has not previously been developed and validated. Expand
Critically ill polyneuropathy: electrophysiological studies and differentiation from Guillain-Barré syndrome.
TLDR
The analysis showed that the two polyneuropathies are likely to be separate entities that can be distinguished in most instances by the predisposing illness, electrophysiological features and cerebrospinal fluid results. Expand
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