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Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer
Cisplatin resistance remains one of the major obstacles when treating epithelial ovarian cancer. Because oxaliplatin and nedaplatin are effective against cisplatin-resistant ovarian cancer inExpand
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HPIP: a predictor of lymph node metastasis and poor survival in cervical cancer
Background The aim of this study was to explore the relationships of HPIP expression status with the clinicopathological variables and survival outcomes of patients with cervical cancer (CC). MethodsExpand
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Upregulation of histone H3K9 methylation in fetal endothelial cells from preeclamptic pregnancies
  • W. Sheng, Yang Gu, +5 authors Yuping Wang
  • Medicine
  • Journal of cellular physiology
  • 23 July 2020
Adverse intrauterine environment has been considered a predisposing factor for fetal programming in preeclampsia. Using human umbilical vein endothelial cells (HUVECs), we specifically explored ifExpand
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Downregulation of miR-126-3p expression contributes to increased inflammatory response in placental trophoblasts in preeclampsia.
  • Xiaodan Chu, Yang Gu, +6 authors Yuping Wang
  • Medicine
  • Journal of reproductive immunology
  • 1 February 2021
MiR-126-3p is a prototype of an endothelial miRNA and has protective effects on endothelial cells. However, little is known about the effects of miR-126-3p on placental trophoblasts. In the presentExpand