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Effects of BSO and DEM on thiol-level and radiosensitivity in HeLa cells.
Radioprotection by glutathione esters and cysteamine in normal and glutathione-depleted mammalian cells.
It seems that in this respect cysteamine cannot fully substitute for endogenous GSH, as its radioprotection could not be mediated by an increase of intracellular GSH.
Protection against X-irradiation by some orally administered compounds.
A number of compounds were studied that protected mice against LD50/30 after X-irradiation, but blood taken from mice that had been treated with these protective compounds provided virtually no protection of HeLa cells in vitro, whereas when blood from cysteamine treated mice was tested in vivo, protection could be demonstrated.
Endogenous versus exogenous thiols in radioprotection.