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- Publications
- Influence
Homocitrulline and Homoarginine Synthesis from Lysine
After the injection of L-lysine and uniformly labeled L-lysine-carbon-14 into the rat, labeled homocitrulline and homoarginine are found in the liver and kidney. The ingestion of lysine by seven… Expand
Homoarginine synthesis by rat kidney.
- W. Ryan, R. J. Johnson, S. Dimari
- Chemistry, Medicine
- Archives of biochemistry and biophysics
- 1 May 1969
Abstract Lysine is transamidinated by enzymes of the kidney to form a compound with the same Chromatographic mobility as homoarginine. The characteristics of the reaction suggest that the enzyme is… Expand
Inhibition of Cell Growth in vitro by Adenosine 3', 5'-Monophosphate
- W. Ryan, M. Heidrick
- Chemistry, Medicine
- Science
- 27 December 1968
Adenosine 3',5'-monophosphate, at a concentration of 40 micrograms per milliliter, inhibits the growth of HeLa and strain L cells in culture. The inhibition becomes progressively greater during the… Expand
Lysine, homocitrulline, and homoarginine metabolism by the isolated perfused rat liver.
- W. Ryan, A. Barak, R. J. Johnson
- Biology, Medicine
- Archives of biochemistry and biophysics
- 1 February 1968
The metabolism of lysine, homocitrulline, and homoarginine in the isolated, perfused liver was investigated. Following the addition of 4 mmoles of lysine to the perfusate, homocitrulline but not… Expand
Antibody stimulation of benzo(a)pyrene carcinogenesis.
- G. L. Curtis, W. Ryan, F. Stenbäck
- Chemistry, Medicine
- Cancer letters
- 1978
Benzo(a)pyrene (BP) was conjugated to horse serum albumin (HSA) and then attached to aldehyde fixed human erythrocytes. These cells were used in a passive hemagglutination test to measure BP… Expand
Phenylalanine conversion to tyrosine by the human fetal liver.
Abstract Immediately after death of five immature human fetuses, dl -phenylalanine-3-C 14 was infused into the liver via the umbilical vein The livers were analyzed for tyrosine by ion-exchange… Expand
Amino Acids and Ammonia of Fetal Calf Serum During Storage.∗
Summary 1. Unnltered fetal calf serum undergoes no change in growth-promoting activity during storage at 5° for 3 months. Six days' storage at 37° results in a loss of activity. 2. Incubation at 37°… Expand
Sample preparation for chromatography of amino acids.
- W. Ryan
- Medicine
- The American journal of medical technology
- 1973
Initiation-promotion skin carcinogenesis: inhibition by cyclic and non-cyclic nucleotides.
- G. L. Curtis, F. Stenback, W. Ryan
- Chemistry, Medicine
- Cancer letters
- 1 April 1979
The effect of nucleotides on initiation-promotion skin carcinogenesis in Swiss mice was investigated. Cyclic AMP was given before initiation with DMBA, between initiation and promotion, and at the… Expand