• Publications
  • Influence
Homocitrulline and Homoarginine Synthesis from Lysine
After the injection of L-lysine and uniformly labeled L-lysine-carbon-14 into the rat, labeled homocitrulline and homoarginine are found in the liver and kidney. The ingestion of lysine by sevenExpand
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Homoarginine synthesis by rat kidney.
Abstract Lysine is transamidinated by enzymes of the kidney to form a compound with the same Chromatographic mobility as homoarginine. The characteristics of the reaction suggest that the enzyme isExpand
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Inhibition of Cell Growth in vitro by Adenosine 3', 5'-Monophosphate
Adenosine 3',5'-monophosphate, at a concentration of 40 micrograms per milliliter, inhibits the growth of HeLa and strain L cells in culture. The inhibition becomes progressively greater during theExpand
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Lysine, homocitrulline, and homoarginine metabolism by the isolated perfused rat liver.
The metabolism of lysine, homocitrulline, and homoarginine in the isolated, perfused liver was investigated. Following the addition of 4 mmoles of lysine to the perfusate, homocitrulline but notExpand
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Antibody stimulation of benzo(a)pyrene carcinogenesis.
Benzo(a)pyrene (BP) was conjugated to horse serum albumin (HSA) and then attached to aldehyde fixed human erythrocytes. These cells were used in a passive hemagglutination test to measure BPExpand
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Phenylalanine conversion to tyrosine by the human fetal liver.
  • W. Ryan, W. Orr
  • Biology, Medicine
  • Archives of biochemistry and biophysics
  • 1 March 1966
Abstract Immediately after death of five immature human fetuses, dl -phenylalanine-3-C 14 was infused into the liver via the umbilical vein The livers were analyzed for tyrosine by ion-exchangeExpand
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Amino Acids and Ammonia of Fetal Calf Serum During Storage.∗
  • W. Ryan, C. Cardin
  • Chemistry, Medicine
  • Proceedings of the Society for Experimental…
  • 1 October 1966
Summary 1. Unnltered fetal calf serum undergoes no change in growth-promoting activity during storage at 5° for 3 months. Six days' storage at 37° results in a loss of activity. 2. Incubation at 37°Expand
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Sample preparation for chromatography of amino acids.
  • W. Ryan
  • Medicine
  • The American journal of medical technology
  • 1973
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Initiation-promotion skin carcinogenesis: inhibition by cyclic and non-cyclic nucleotides.
The effect of nucleotides on initiation-promotion skin carcinogenesis in Swiss mice was investigated. Cyclic AMP was given before initiation with DMBA, between initiation and promotion, and at theExpand
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