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Synthetic Biology Moving into the Clinic
Synthetic biology is an emerging field focused on engineering biomolecular systems and cellular capabilities for a variety of applications. Substantial progress began a little over a decade ago withExpand
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Artificial cells: building bioinspired systems using small-scale biology.
Artificial cells have generated much interest since the concept was introduced by Aleksandr Oparin in the 1920s, and they have had an impact on the pharmaceutical and biotechnology industry inExpand
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Low-cost feedback-controlled syringe pressure pumps for microfluidics applications
We present a low-cost ($110) syringe pressure pump that uses feedback control to regulate the pressure into microfluidic chips. Expand
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Probing Cellular Dynamics with a Chemical Signal Generator
Observations of material and cellular systems in response to time-varying chemical stimuli can aid the analysis of dynamic processes. We describe a microfluidic “chemical signal generator,” aExpand
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Programming Surface Chemistry with Engineered Cells.
We have developed synthetic gene networks that enable engineered cells to selectively program surface chemistry. E. coli were engineered to upregulate biotin synthase, and therefore biotin synthesis,Expand
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Creating biological nanomaterials using synthetic biology
  • M. Rice, W. Ruder
  • Materials Science, Medicine
  • Science and technology of advanced materials
  • 3 December 2013
Abstract Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fieldsExpand
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Three-dimensional microfiber devices that mimic physiological environments to probe cell mechanics and signaling.
Many physiological systems are regulated by cells that alter their behavior in response to changes in their biochemical and mechanical environment. These cells experience this dynamic environmentExpand
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Exploring Host-Microbiome Interactions using an in Silico Model of Biomimetic Robots and Engineered Living Cells
The microbiome’s underlying dynamics play an important role in regulating the behavior and health of its host. In order to explore the details of these interactions, we created an in silico model ofExpand
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Sudden motility reversal indicates sensing of magnetic field gradients in Magnetospirillum magneticum AMB-1 strain
Many motile unicellular organisms have evolved specialized behaviors for detecting and responding to environmental cues such as chemical gradients (chemotaxis) and oxygen gradients (aerotaxis).Expand
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Controlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approach
Herein, we demonstrate the control of magnetotactic bacteria through the application of magnetic field gradients with real-time visualization. We accomplish this control by integrating a pair ofExpand
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