W. Rosenbrook

Publications44
h-index13
Citations597
Highly Influential Citations9
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Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro.
TLDR
Two newly synthesized carbocyclic oxetanocin analogs, (+/-)-9-[(1 beta,2 alpha,3 beta)-2,3-bis(hydroxymethyl)-1-cyclobutyl]guanine and cyclobut-G, tested for activity against the infectivity of human immunodeficiency virus (HIV) in vitro have a certain level of in vitro toxicity. Expand
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.
TLDR
The synthesis and broad-spectrum antiviral activity of two oxetanocin 11 analogues are reported, capable of controlling the replication of both HIV and herpesviruses. Expand
DEATH FROM "WASP" STING.
Structure of chelocardin, a novel tetracycline antibiotic.
Hymenoptera: Pure Venom from Bees, Wasps, and Hornets
Pure venom can be obtained from bees, wasps, and hornets by electrical stimulation with inexpensive apparatus.
Disc Electrophoresis of Hymenoptera Venoms and Body Proteins
The venom proteins of honey bee, Polistes wasp, yellow hornet, and yellow jacket are similar but not identical. Extracts of venom sacs and whole insects contain several proteins not found in the pure… Expand
THE VENOM OF THE MUD-DAUBER WASP. 3. SCELIPHRON CAEMENTARIUM: GENERAL CHARACTER.
TLDR
This is the first investigation of any wasp venom to deal with the pure venom as opposed to a venom-apparatus extract and reveals a minimum of 15 compounds not present in the venom itself, thus emphasizing the value of studies based on the natural venom. Expand
Studies on the biosynthesis of the erythromycins. II. Isolation and structure of a biosynthetic intermediate, 6-deoxyerythronolide B.
Structure of chelocardin, a novel tetracycline antibiotic.
THE VENOM OF THE MUD-DAUBER WASP. II. SCELIPHRON CAEMENTARIUM: PROTEIN CONTENT.
Gel filtration of Sceliphron caementarium venom, obtained by electrical excitation, has shown an unexpectedly small protein fraction of the dried venom. Disc electrophoresis was used to separate five… Expand
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