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Simultaneous determination of ethylene glycol and glycolic acid in serum by gas chromatography-mass spectrometry.
We describe a gas chromatographic-mass spectrometric (GC-MS) procedure for the simultaneous determination of ethylene glycol (EG) and its major toxic metabolite, glycolic acid (GA), in serum. In thisExpand
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Simultaneous determination of ethylene glycol and its major toxic metabolite, glycolic acid, in serum by gas chromatography.
We developed a gas-chromatographic procedure for the simultaneous determination of ethylene glycol (EG) and its major toxic metabolite, glycolic acid (GA), suitable for clinical use in instances ofExpand
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Ethylene Glycol Toxicity: The Role of Serum Glycolic Acid In Hemodialysis
Objective: To correlate serum glycolic acid levels with clinical severity and outcome in ethylene glycol poisoning and to determine if glycolic acid levels are predictive of renal failure and theExpand
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Interference by glycolic acid in the Beckman synchron method for lactate: a useful clue for unsuspected ethylene glycol intoxication.
In the differential evaluation of patients with high anion gap metabolic acidosis of unknown origin, lactate determinations are frequently performed. For patients who ingest ethylene glycol (presentExpand
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Ethylene glycol poisoning: quintessential clinical toxicology; analytical conundrum.
  • W. Porter
  • Medicine
  • Clinica chimica acta; international journal of…
  • 2012
Ethylene glycol poisoning is a medical emergency that presents challenges both for clinicians and clinical laboratories. Untreated, it may cause morbidly or death, but effective therapy is available,Expand
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gamma-Hydroxybutyrate intoxication and overdose.
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Gas-chromatographic determination of ethylene glycol in serum.
We describe a new gas-chromatographic procedure for ethylene glycol in serum, determined as the cyclic phenylboronate ester. The method is rapid, requires only 100 microL of serum, and either an OV-1Expand
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Elevated lactate in ethylene glycol poisoning: True or false?
BACKGROUND There have been an increasing number of reports on false increase of lactate in ethylene glycol poisoning. We recently encountered two cases of ethylene glycol poisoning with very highExpand
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Hemodialysis clearance of pentobarbital during continuous infusion.
The hemodialysis clearance of pentobarbital during continuous infusion was determined in a 34-year-old man in acute renal failure. Pentobarbital specimens were obtained simultaneously from arterialExpand
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Application of nitrous acid deamination of hexosamines to the simultaneous GLC determination of neutral and amino sugars in glycoproteins.
  • W. Porter
  • Chemistry, Medicine
  • Analytical biochemistry
  • 1975
Abstract A method is described for simultaneous gas chromatographic analysis of neutral sugars and hexosamines in glycoproteins. Sugars are hydrolyzed with the aid of Dowex 50-X2 (H + ) resin and theExpand
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