• Publications
  • Influence
Pharmacokinetics of duloxetine hydrochloride enteric-coated tablets in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study.
BACKGROUND Duloxetine hydrochloride is a balanced selective serotonin and norepinephrine reuptake inhibitor. Despite being widely used for the treatment of major depressive disorder in China, littleExpand
  • 24
  • 1
Multiple dose pharmacokinetics of quetiapine and some of its metabolites in Chinese suffering from schizophrenia.
AIM To study the multiple dose pharmacokinetics of quetiapine and its sulfoxide-, 7-hydroxy-, 7-hydroxy-N-dealkyl-metabolites in Chinese suffering from schizophrenia. METHODS Twenty-one patientsExpand
  • 15
  • 1
Validated HPLC-MS/MS Method for Simultaneous Determination of Curcumin and Piperine in Human Plasma
Purpose: To develop a sensitive and rapid method for the simultaneous determination of curcumin and piperine in human plasma. Methods: The method was based on high-performance liquid chromatographyExpand
  • 18
  • 1
[The effect of tetramethylpyrazine on the pharmacokinetics of intragastrically administered cyclosporine A in rats].
AIM To investigate the possible effect of tetramethylpyrazine (TMP), an active ingredient of a commonly used Chinese herb, on the pharmacokinetics of cyclosporine A (CsA) by intragastricExpand
  • 1
Effect of daidzein on CYP1A2 activity and pharmacokinetics of theophylline in healthy volunteers
ObjectiveTo examine the potential effect of daidzein on CYP1A2 activity and on the pharmacokinetics of theophylline by inhibiting its metabolism.MethodsThe experiment was conducted in a single-blind,Expand
  • 40
Upregulation of Rat Renal Cortical Organic Anion Transporter (OAT1 and OAT3) Expression in Response to Ischemia/Reperfusion Injury
Background/Aims: Renal organic anion transporters (OAT1 and OAT3) localized in the basolateral membrane mediate the uptake of organic anions from the blood into proximal tubules. This study aimed toExpand
  • 15
Validated HILIC-MS/MS assay for determination of vindesine in human plasma: Application to a population pharmacokinetic study.
  • R. Zhu, Huan-De Li, +4 authors W. Peng
  • Medicine, Chemistry
  • Journal of pharmaceutical and biomedical analysis
  • 5 August 2014
The first HILIC-tandem mass spectrometry (MS/MS) method for determination of vindesine (VDS) in human plasma using vinorelbine as an internal standard (IS) has been developed and validated. PlasmaExpand
  • 10
Effect of erythromycin on metabolism of quetiapine in Chinese suffering from schizophrenia
ObjectiveTo study the effect of erythromycin on metabolism of quetiapine in Chinese suffering from schizophrenia.MethodsNineteen patients received multiple doses of quetiapine (200 mg, twice daily)Expand
  • 21
Validated LC-MS/MS assay for the quantitative determination of nalbuphine in human plasma and its application to a pharmacokinetic study.
A solid-phase extraction-liquid chromatographic-tandem mass spectrometry method for the determination of nalbuphine concentrations in human plasma has been developed. Samples (1 mL) were extractedExpand
  • 14
Determination of talinolol in human plasma by high performance liquid chromatography-electrospray ionization mass spectrometry: application to pharmacokinetic study.
  • J. He, B. Terhaag, +7 authors W. Peng
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical…
  • 15 June 2007
A rapid and sensitive method for determination and screening in human plasma of talinolol is described using propranolol as the internal standard. The analytes in plasma were extracted byExpand
  • 6