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Thermoreversible Pluronic® F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies
Purpose To develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic® F127 gel) for controlled release and improved antitumorExpand
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Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response.
Mitochondrion-orientated transportation of smart liposomes has been developed as a promising strategy to deliver anticancer drugs directly to tumor sites, and these have a tremendous potential forExpand
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Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery.
In this study liposome coated with low molecular weight chitosan (LCH) was proposed and investigated its in vitro and in vivo properties, and its potential use in ocular drug delivery was evaluated.Expand
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Study of an alginate/HPMC-based in situ gelling ophthalmic delivery system for gatifloxacin.
The poor bioavailability and therapeutic response exhibited by conventional ophthalmic solutions due to rapid pre-corneal elimination of the drug may be overcome by the use of in situ gel-formingExpand
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Preparation and Evaluation of SEDDS and SMEDDS Containing Carvedilol
ABSTRACT A new self-emulsifying drug delivery system (SEDDS) and self-microemulsifying drug delivery system (SMEDDS) have been developed to increase the solubility, dissolution rate, and, ultimately,Expand
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Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits.
  • H. Xu, L. He, +4 authors W. Pan
  • Chemistry, Medicine
  • Journal of controlled release : official journal…
  • 16 November 2009
Free-flowing proliposomes which contained vinpocetine were prepared successfully to increase the oral bioavailability of vinpocetine. In this study the proliposomes were prepared by a novel methodExpand
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Fabrication of Carvedilol Nanosuspensions Through the Anti-Solvent Precipitation–Ultrasonication Method for the Improvement of Dissolution Rate and Oral Bioavailability
  • D. Liu, H. Xu, +5 authors W. Pan
  • Materials Science, Medicine
  • AAPS PharmSciTech
  • 13 January 2012
The present study aims to prepare carvedilol (CAR) nanosuspensions using the anti-solvent precipitation–ultrasonication technique to improve its dissolution rate and oral bioavailability.Expand
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Preparation and investigation of controlled-release glipizide novel oral device with three-dimensional printing.
  • Qijun Li, Haoyang Wen, +7 authors W. Pan
  • Materials Science, Medicine
  • International journal of pharmaceutics
  • 15 June 2017
The purpose of this study was to explore the feasibility of combining fused deposition modeling (FDM) 3D printing technology with hot melt extrusion (HME) to fabricate a novel controlled-release drugExpand
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The potential use of novel chitosan-coated deformable liposomes in an ocular drug delivery system.
In this study, novel chitosan-coated deformable liposomes (DL-CS) were proposed as an ocular drug delivery system to prolong pre-corneal retention, and improve transcorneal penetration andExpand
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Development and characterization of nanostructured lipid carriers based chitosan thermosensitive hydrogel for delivery of dexamethasone.
This study aims to explore a novel composite thermosensitive in situ gelling formulation which the nanostructured lipid carriers (NLC) was incorporated into hydroxypropyltrimethyl ammonium chlorideExpand
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